The relationship of major depressive disorder to bipolar disorsder: Continuous or discontinuous?

被引：21
作者：
Benazzi F. [1 ]
机构：
[1] 48010 Castiglione di Cervia RA
来源：
Current Psychiatry Reports | 2005年 / 7卷 / 6期
关键词：
Bipolar Disorder; Mood Disorder; Major Depressive Disorder; Major Depressive Episode; Bipolar Spectrum;
D O I：
10.1007/s11920-005-0068-6
中图分类号：
学科分类号：
摘要：
Recent studies have questioned current diagnostic systems that split mood disorders into the independent categories of bipolar disorders and depressive disorders. The current classification of mood disorders runs against Kraepelin's unitary view of manic-depressive insanity (illness). The main findings of recent studies supporting a continuity between bipolar disorders (mainly bipolar II disorder) and major depressive disorder are presented. The features supporting a continuity between bipolar II disorder and major depressive disorder currently are 1) depressive mixed states (mixed depression) and dysphoric (mixed) hypomania (opposite polarity symptoms in the same episode do not support a splitting of mood disorders); 2) family history (major depressive disorder is the most common mood disorder in relatives of bipolar probands); 3) lack of points of rarity between the depressive syndromes of bipolar II disorder and major depressive disorder; 4) major depressive disorder with bipolar features such as depressive mixed states, young onset age, atypical features, bipolar family history, irritability, racing thoughts, and psychomotor agitation; 5) a high proportion of major depressive disorders shifting to bipolar disorders during long-term follow-up; 6) a high proportion of major depressive disorders with history of manic and hypomanic symptoms; 7) factors of hypomania present in major depressive disorder episodes; 8) recurrent course of major depressive disorder; and 9) depressive symptoms much more common than manic and hypomanic symptoms in the course of bipolar disorders. Copyright © 2005 by Current Science Inc.
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页码：462 / 470
页数：8
相关论文
共 101 条
[61]  
Akiskal H.S., Benazzi F., Perugi G., Rihmer Z., Agitated "unipolar" depression re-conceptualized as a depressive mixed state: Implications for the antidepressant-suicide controversy, J Affect Disord, 85, pp. 245-258, (2005)
[62]  
Benazzi F., Akiskal H.S., Clinical and factor analytic-validation of depressive mixed states: A report from the Ravenna-San Diego collaboration, Curr Opin Psychiatry, 16, SUPPL. 2, (2003)
[63]  
Sato T., Bottlender R., Kleindienst N., Moller H.J., Irritable psychomotor elation in depressed inpatients: A factor validation of mixed depression, J Affect Disord, 84, pp. 187-196, (2005)
[64]  
Hirschfeld R.M., Calabrese J.R., Weissman M.M., Et al., Screening for bipolar disorder in the community, J Clin Psychiatry, 64, pp. 1130-1131, (2003)
[65]  
Judd L.L., Akiskal H.S., The prevalence and disability of bipolar spectrum disorders in the US population: Re-analysis of the ECA database taking into account subthreshold cases, J Affect Disord, 73, pp. 123-131, (2003)
[66]  
Rybakowski J.K., Suwalska A., Lojko D., Et al., Bipolar mood disorders among Polish psychiatric outpatients treated for major depression, J Affect Disord, 84, pp. 141-147, (2005)
[67]  
Smith D.J., Harrison N., Muir W., Blackwood D.H., The high prevalence of bipolar spectrum disorders in young adults with recurrent depression: Toward an innovative diagnostic framework, J Affect Disord, 84, pp. 167-178, (2005)
[68]  
Benazzi F., High frequency of bipolar spectrum in outpatients with depression, Can J Psychiatry, 49, pp. 279-280, (2004)
[69]  
Benazzi F., Frequency of bipolar spectrum in 111 private practice depression outpatients, Eur Arch Psychiatry Clin Neurosci, 253, pp. 203-208, (2003)
[70]  
Bottlender R., Sato T., Kleindienst N., Et al., Mixed depressive features predict maniform switch during treatment of depression in bipolar I disorder, J Affect Disord, 78, pp. 149-152, (2004)
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