Multicenter phase II clinical trial of preoperative capecitabine with concurrent radiotherapy in patients with locally advanced rectal cancer

被引:0
作者
Manuel de las Heras
Fernando Arias
Rosario del Moral-Avila
Jaime Gómez-Millán
Encarnación Jiménez
Amadeo Wals
Jose Luis Tisaire
Ma Pino Alcantara
机构
[1] Hospital Clínico Universitario San Carlos,Head of the Department Radiation Oncology
[2] Hospital de Navarra,Department Radiation Oncology
[3] Hospital Virgen de las Nieves,Head of the Department Radiation Oncology
[4] Hospital Virgen de la Victoria,Radiation Oncology Department
[5] Hospital de Jerez,Head of Department Clinical Oncology
[6] Hospital Carlos Haya,Radiation Oncology Department
[7] Hospital de Alcazar,Radiotherapy Service
[8] Hospital Clínico San Carlos,Radiation Oncology Department
来源
Clinical and Translational Oncology | 2013年 / 15卷
关键词
Rectal cancer; Capecitabine; Chemoradiotherapy; Radiation; Neoadjuvant treatment;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:294 / 299
页数:5
相关论文
共 46 条
[1]  
Krook JE(1991)Effective surgical adjuvant therapy for high-risk rectal carcinoma N Engl J Med 324 709-715
[2]  
Moertel CG(2004)Preoperative versus postoperative chemoradiotherapy for rectal cancer N Engl J Med 351 1731-1740
[3]  
Gunderson LL(2007)Locally advanced rectal cancer: what is the evidence for induction chemoradiation? Oncologist 12 1309-1318
[4]  
Glynne-Jones R(1998)Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. Meta-analysis group in cancer J Clin Oncol 16 301-308
[5]  
Harrison M(2001)Thymidine phosphorylase (TP) activation: convenience through innovation Oncologist 6 1-2
[6]  
Piedbois P(2001)Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study J Clin Oncol 19 4097-4106
[7]  
Rougier P(1997)Patient preferences for oral versus intravenous palliative chemotherapy J Clin Oncol 15 5-110
[8]  
Buyse M(2001)Answering patients’ needs: oral alternatives to intravenous therapy Oncologist 6 6-12
[9]  
Cutsem E(2006)Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial Croat Med J 47 693-700
[10]  
Cunningham D(2002)Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer J Clin Oncol 20 3983-3991