A phase 2 study of intravenous panobinostat in patients with castration-resistant prostate cancer

[1] Albany C(2011)Epigenetics in prostate cancer Prostate Cancer 2011 580318-713

[2] Alva AS(2001)Histone deacetylase and DNA methyltransferase in human prostate cancer Biochem Biophys Res Commun 287 705-8575

[3] Aparicio AM(2003)Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth Mol Cell Biol 23 8563-309

[4] Singal R(2008)The role of histone deacetylases in prostate cancer Epigenetics 3 300-222

[5] Yellapragada S(2008)DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines Prostate 68 210-1266

[6] Sonpavde G(2005)Global histone modification patterns predict risk of prostate cancer recurrence Nature 435 1262-610

[7] Hahn NM(2008)Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy Br J Cancer 98 604-179

[8] Patra SK(2010)Application of histone modification in the risk prediction of the biochemical recurrence after radical prostatectomy Asian J Androl 12 171-4890

[9] Patra A(2007)Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90 Clin Cancer Res 13 4882-10465

[10] Dahiya R(2007)Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity Cancer Res 67 10455-549

[1] Albany C(2011)Epigenetics in prostate cancer Prostate Cancer 2011 580318-713

[2] Alva AS(2001)Histone deacetylase and DNA methyltransferase in human prostate cancer Biochem Biophys Res Commun 287 705-8575

[3] Aparicio AM(2003)Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth Mol Cell Biol 23 8563-309

[4] Singal R(2008)The role of histone deacetylases in prostate cancer Epigenetics 3 300-222

[5] Yellapragada S(2008)DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines Prostate 68 210-1266

[6] Sonpavde G(2005)Global histone modification patterns predict risk of prostate cancer recurrence Nature 435 1262-610

[7] Hahn NM(2008)Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy Br J Cancer 98 604-179

[8] Patra SK(2010)Application of histone modification in the risk prediction of the biochemical recurrence after radical prostatectomy Asian J Androl 12 171-4890

[9] Patra A(2007)Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90 Clin Cancer Res 13 4882-10465

[10] Dahiya R(2007)Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity Cancer Res 67 10455-549