The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

被引:0
作者
Alexandra Winkeler
Raphael Boisgard
Ali R. Awde
Albertine Dubois
Benoit Thézé
Jinzi Zheng
Luisa Ciobanu
Frédéric Dollé
Thomas Viel
Andreas H. Jacobs
Bertrand Tavitian
机构
[1] Université Paris Sud,Inserm, U1023, Laboratoire d’Imagerie Moléculaire Expérimentale
[2] CEA,European Institute for Molecular Imaging (EIMI)
[3] DSV,undefined
[4] I2BM,undefined
[5] NeuroSpin,undefined
[6] LRMN,undefined
[7] Westfälische Wilhelm-Universität Münster (WWU),undefined
[8] CEA,undefined
[9] I2BM,undefined
[10] SHFJ,undefined
来源
European Journal of Nuclear Medicine and Molecular Imaging | 2012年 / 39卷
关键词
Glioma; Translocator protein; TSPO; Microglia; Positron emission tomography; Peripheral benzodiazepine receptor; [; F]DPA-714;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:811 / 823
页数:12
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  • [41] Olson JM(2010)PET imaging of gliomas using novel tracers: a sleeping beauty waiting to be kissed Expert Rev Anticancer Ther 10 609-613
  • [42] Junck L(2007)A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation J Neurochem 102 2118-2131
  • [43] Young AB(2009)Quantification of translocator protein (18 kDa) in the human brain with PET and a novel radioligand, (18)F-PBR06 J Nucl Med 50 1047-1053
  • [44] Penney JB(2008)Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors Neuroimage 39 1289-1298
  • [45] Mancini WR(2009)Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas J Neurooncol 94 299-312
  • [46] Starosta-Rubinstein S(2010)The brain tumor window model: a combined cranial window and implanted glioma model for evaluating intraoperative contrast agents Neurosurgery 66 736-743
  • [47] Ciliax BJ(1996)Middle cerebral artery occlusion in Wistar and Fischer-344 rats: functional and morphological assessment of the model J Cereb Blood Flow Metab 16 296-302
  • [48] Penney JB(2008)Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation Neuroimage 40 43-52
  • [49] McKeever P(2011)Mixed-affinity binding in humans with 18-kDa translocator protein ligands J Nucl Med 52 24-32
  • [50] Young AB(2010)Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation J Cereb Blood Flow Metab 30 1608-1618