Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6

被引：0
|
作者：
Patrick Yu-Wai-Man
Grainne Gorman
David E. Bateman
R. John Leigh
Patrick F. Chinnery
机构：
[1] The Medical School,Mitochondrial Research Group, School of Neurology, Neurobiology and Psychiatry
[2] Newcastle University,Dept. of Neurology
[3] North Cumbria Acute NHS Trust,Dept. of Neurology
[4] Veterans Affairs Medical Center and Case Western Reserve University,Dept. of Ophthalmology
[5] Royal Victoria Infirmary,undefined
来源：
Journal of Neurology | 2009年 / 256卷
关键词：
spinocerebellar ataxia; stereopsis; nystagmus; ocular motility; vertigo; vestibular;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Spinocerebellar ataxia type 6 (SCA6) is a calcium channelopathy due to a pathological CAG repeat expansion in CACNL1A4. Patients frequently describe paroxysmal vertigo early in the disease course, but it is not clear whether this is central or labyrinthine in origin. To address this issue we studied 21 SCA6 patients. Symptoms of vertigo were defined using a structured questionnaire. Signs were recorded during a standardised bed-side vestibular examination that included systematic positional testing with Frenzel goggles.
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页码：78 / 82
页数：4
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