Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6

被引：0

作者：

Patrick Yu-Wai-Man

Grainne Gorman

David E. Bateman

R. John Leigh

Patrick F. Chinnery

机构：

[1] The Medical School,Mitochondrial Research Group, School of Neurology, Neurobiology and Psychiatry

[2] Newcastle University,Dept. of Neurology

[3] North Cumbria Acute NHS Trust,Dept. of Neurology

[4] Veterans Affairs Medical Center and Case Western Reserve University,Dept. of Ophthalmology

[5] Royal Victoria Infirmary,undefined

来源：

Journal of Neurology | 2009年 / 256卷

关键词：

spinocerebellar ataxia; stereopsis; nystagmus; ocular motility; vertigo; vestibular;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Spinocerebellar ataxia type 6 (SCA6) is a calcium channelopathy due to a pathological CAG repeat expansion in CACNL1A4. Patients frequently describe paroxysmal vertigo early in the disease course, but it is not clear whether this is central or labyrinthine in origin. To address this issue we studied 21 SCA6 patients. Symptoms of vertigo were defined using a structured questionnaire. Signs were recorded during a standardised bed-side vestibular examination that included systematic positional testing with Frenzel goggles.

引用

页码：78 / 82

页数：4

共 50 条

[1] Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6
Yu-Wai-Man, Patrick
Gorman, Grainne
Bateman, David E.
Leigh, R. John
Chinnery, Patrick F.
JOURNAL OF NEUROLOGY, 2009, 256 (01) : 78 - 82
[2] Spinocerebellar ataxia type 6 with positional vertigo and acetazolamide responsive episodic ataxia
Jen, JC
Yue, Q
Karrim, J
Nelson, SF
Baloh, RW
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1998, 65 (04): : 565 - 568
[3] Oculomotor abnormalities in myoclonic tremor: a comparison with spinocerebellar ataxia type 6
Bour, L. J.
van Rootselaar, A. F.
Koelman, J. H. T. M.
Tijssen, M. A. J.
BRAIN, 2008, 131 : 2295 - 2303
[4] Evolution of the vestibular function during head impulses in spinocerebellar ataxia type 6
Lee, Sun-Uk
Kim, Ji-Soo
Kim, Hyo-Jung
Choi, Jeong-Yoon
Park, Ji-Yun
Kim, Jong-Min
Yang, Xu
JOURNAL OF NEUROLOGY, 2020, 267 (06) : 1672 - 1678
[5] Evolution of the vestibular function during head impulses in spinocerebellar ataxia type 6
Sun-Uk Lee
Ji-Soo Kim
Hyo-Jung Kim
Jeong-Yoon Choi
Ji-Yun Park
Jong-Min Kim
Xu Yang
Journal of Neurology, 2020, 267 : 1672 - 1678
[6] Positional vertigo and macroscopic downbeat positioning nystagmus in spinocerebellar ataxia type 6 (SCA6)
Ichiro Yabe
Hidenao Sasaki
Norihito Takeichi
Asako Takei
Takeshi Hamada
Kikuro Fukushima
Kunio Tashiro
Journal of Neurology, 2003, 250 : 440 - 443
[7] Positional vertigo and macroscopic downbeat positioning nystagmus in spinocerebellar ataxia type 6 (SCA6)
Yabe, I
Sasaki, H
Takeichi, N
Takei, A
Hamada, T
Fukushima, K
Tashiro, K
JOURNAL OF NEUROLOGY, 2003, 250 (04) : 440 - 443
[8] Visual Suppression is Impaired in Spinocerebellar Ataxia Type 6 but Preserved in Benign Paroxysmal Positional Vertigo
Kishi, Masahiko
Sakakibara, Ryuji
Yoshida, Tomoe
Yamamoto, Masahiko
Suzuki, Mitsuya
Kataoka, Manabu
Tsuyusaki, Yohei
Tateno, Akihiko
Tateno, Fuyuki
DIAGNOSTICS, 2012, 2 (04): : 52 - 56
[9] Dystonia in spinocerebellar ataxia type 6
Sethi, KD
Jankovic, J
MOVEMENT DISORDERS, 2002, 17 (01) : 150 - 153
[10] SPINOCEREBELLAR ATAXIA TYPE 6 IN BRAZIL
Teive, Helio A. G.
Munhoz, Renato Puppi
Raskin, Salmo
Werneck, Lineu Cesar
ARQUIVOS DE NEURO-PSIQUIATRIA, 2008, 66 (3B) : 691 - 694

← 1 2 3 4 5 →