Vasculitis - Classification and immunopathogenesis

被引：2

作者：

Wagner N. ^{[1
,2
]}

机构：

[1] Westfälisches Kinderzentrum Dortmund, Klinikum, 44137 Dortmund

来源：

Monatsschrift Kinderheilkunde | 2006年 / 154卷 / 9期

关键词：

Cytotoxicity; Endothelial cell; Hypersensitivity reaction; Immune complexes; Vasculitis;

D O I：

10.1007/s00112-006-1392-6

中图分类号：

学科分类号：

摘要：

Vasculitides are immune mediated, inflammatory reactions of the vessel wall the etiology of which is mostly unclear. The clinical spectrum is wide: harmless, mainly cutaneous courses of Henoch-Schönlein purpura as well as life-threatening courses with renal failure in microscopic polyangiitis occur. Classification systems use the size of the afflicted vessel, differentiate vasculitides by histopathological findings and divide them into primary and secondary groups, the latter being mediated by connective tissue disease (e.g. systemic lupus erythomatosus). The immunopathogenesis may be explained by the four different forms of hypersensitivity reactions. © 2006 Springer Medizin Verlag.

引用

页码：859 / 864

页数：5

共 6 条

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