Age-related changes in the cerebrospinal fluid level of β-endorphin and substance PShort Communication

被引：0

作者：

S. Nagamitsu

T. Matsuishi

H. Komori

Y. Yamashita

H. Eguchi

K. Ichikawa

T. Fujimoto

H. Kato

机构：

[1] Department of Pediatrics and Child Health,

[2] Kurume University School of Medicine,undefined

[3] Kurume,undefined

[4] ,undefined

[5] Department of Pediatrics,undefined

[6] Emergency Medical Center,undefined

[7] Kitakyushu City Yahata Hospital,undefined

[8] Kitakyusyu,undefined

[9] and,undefined

[10] Fujimoto Children's Hospital,undefined

[11] Ohita,undefined

[12] Japan,undefined

来源：

Journal of Neural Transmission | 1998年 / 105卷

关键词：

Keywords: Cerebrospinal fluid; β-endorphin; substance P; age.;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

To evaluate the early age-related changes in neuropeptides, we have measured the cerebrospinal fluid (CSF) levels of β-endorphin and substance P in young patients over a range of ages. Specimens of CSF were obtained from 39 neurologically normal children, aged 1 month to 10 years of age, and in 9 adult controls. CSF levels of both neuropeptides were observed to peak during the first year of life, and showed a negative correlation with increasing age. A significant positive correlation was observed between the CSF level of β-endorphin and that of substance P.

引用

页码：53 / 58

页数：5

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