Real-world study on microsatellite instability and mismatch repair deficiency testing patterns among patients with metastatic colorectal cancer in Spain

被引：0

作者：

Rocio Garcia-Carbonero

Beatriz González Astorga

Rosario Vidal Tocino

Débora Contreras Toledo

Carles Pericay

Ana Fernández Montes

Esther Falcó

Marta González Cordero

Juan José Reina Zoilo

Vicente Alonso

Nuria Rodríguez Salas

Mireia Gil-Raga

Cristina Santos

David Páez

Beatriz Anton-Pascual

Fernando Aguilar

Pilar Morales

机构：

[1] Hospital Universitario 12 de Octubre,Medical Oncology Department

[2] IIS Imas12,Medical Oncology Department

[3] UCM,Medical Oncology Department

[4] Hospital Universitario Clínico San Cecilio,Medical Oncology Department

[5] Complejo Asistencial Universitario de Salamanca,Medical Oncology Department

[6] IBSAL,Medical Oncology Department

[7] Hospital Universitario Central de Asturias,Medical Oncology Department

[8] ISPA,Medical Oncology Department

[9] Programa Doctorado en Ciencias de la Salud,Medical Oncology Department

[10] Universidad de Oviedo,Medical Oncology Department

[11] Hospital Universitari Parc Taulí,Medical Oncology Department

[12] Complexo Hospitalario Universitario de Ourense,Medical Oncology Department

[13] Hospital Son Llatzer,Medical Oncology Department

[14] Hospital Universitario de Badajoz,Medical Oncology Department

[15] Hospital Universitario Virgen Macarena,Medical Affairs Department

[16] Hospital Universitario Miguel Servet,undefined

[17] Hospital Universitario La Paz,undefined

[18] Hospital General Universitario de Valencia,undefined

[19] Institute Català d’Oncologia IDIBELL,undefined

[20] L’Hospitalet,undefined

[21] U705 (CIBERER),undefined

[22] Hospital de la Santa Creu i Sant Pau,undefined

[23] MSD Spain,undefined

来源：

Clinical and Translational Oncology | 2024年 / 26卷

关键词：

Metastatic colorectal cancer; Microsatellite instability; Mismatch repair deficiency; Microsatellite stable; Real-world evidence;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：864 / 871

页数：7

共 126 条

[1]

Sung H(2021)Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 71 209-249

[2]

Ferlay J(2015)Trends in colorectal cancer mortality in Europe: retrospective analysis of the WHO mortality database BMJ 351 h4970-438

[3]

Siegel RL(2020)Treatment of patients with late-stage colorectal cancer: ASCO resource-stratified guideline JCO Glob Oncol 6 414-70

[4]

Laversanne M(2018)Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO-ESMO initiative endorsed by CSCO, KACO, MOS SSO and TOS Ann Oncol 29 44-2520

[5]

Soerjomataram I(2019)Mismatch repair deficiency/microsatellite instability-high as a predictor for anti-PD-1/PD-L1 immunotherapy efficacy J Hematol Oncol 12 54-19

[6]

Jemal A(2015)PD-1 blockade in tumors with mismatch-repair deficiency N Engl J Med 372 2509-2218

[7]

Ouakrim DA(2020)Phase II open-label study of pembrolizumab in treatment-refractory, microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer: KEYNOTE-164 J Clin Oncol 38 11-670

[8]

Pizot C(2020)Pembrolizumab in microsatellite-instability-high advanced colorectal cancer N Engl J Med 383 2207-1191

[9]

Boniol M(2022)Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study Lancet Oncol 23 659-170

[10]

Malvezzi M(2017)Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study Lancet Oncol 18 1182-32

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