Percutaneous radiofrequency ablation of small hepatocellular carcinoma: long-term results

被引：0

作者：

Luigi Buscarini

Elisabetta Buscarini

Michele Di Stasi

Daniele Vallisa

Pietro Quaretti

Andrea Rocca

机构：

[1] Department of Gastroenterology,

[2] General Hospital,undefined

[3] Via Taverna 49,undefined

[4] 29100 Piacenza,undefined

[5] Italy Tel.: + 39-5 23-30 31 52 Fax: + 39-5 23-30 31 42,undefined

[6] Department of Internal Medicine,undefined

[7] General Hospital,undefined

[8] Via Taverna 49,undefined

[9] 29100 Piacenza,undefined

[10] Italy,undefined

[11] Department of Radiology,undefined

[12] General Hospital,undefined

[13] Via Taverna 49,undefined

[14] 29100 Piacenza,undefined

[15] Italy,undefined

[16] Department of Oncology,undefined

[17] General Hospital,undefined

[18] Via Taverna 49,undefined

[19] 29100 Piacenza,undefined

[20] Italy,undefined

来源：

European Radiology | 2001年 / 11卷

关键词：

Keywords Hepatocellular carcinoma; Radiofrequency ablation; Ultrasonography; Dynamic contrast CT;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The aim of this study was to evaluate the effectiveness and the safety of percutaneous radiofrequency (RF) thermal ablation of hepatocellular carcinoma (HCC) in 88 patients with a long follow-up, and to compare conventional electrodes and expandable electrodes. Eighty-eight patients with 101 hepatocellular carcinoma nodules (≤ 3.5 cm in diameter) underwent RF thermal ablation by means of either conventional electrodes or an expandable electrode. Therapeutic efficacy was evaluated with dynamic contrast CT, serum α-feto protein level, US examination at the end of the treatment, and during follow-up. Complete necrosis was obtained in all tumor nodules in a mean number of 3.3 sessions (tumor treated by conventional electrodes) or 1.5 sessions (tumor treated by expandable electrode). The mean follow-up was 34 months; overall survival rate was 33 % at 5 years. Disease-free survival at 5 years was 3 %; local recurrence rate was 29 % in patients treated with conventional electrodes; 14 % in patients treated with the expandable electrode. Two major complications and 14 minor complications were observed. Radiofrequency thermal ablation in small HCC is very effective with a low percentage of major complications. The use of an expandable electrode substantially reduced the number of treatment sessions but did not modify the overall survival rate and the disease-free survival rate.

引用

页码：914 / 921

页数：7