Quantitative Assessment of CYP2C9 Genetic Polymorphisms Effect on the Oral Clearance of S-Warfarin in Healthy Subjects

被引：0
作者：
Chanan Shaul
Simcha Blotnick
Mordechai Muszkat
Meir Bialer
Yoseph Caraco
机构：
[1] Hadassah-Hebrew University Medical Center,Clinical Pharmacology Unit, Division of Medicine
[2] Hebrew University,Institute of Drug Research, School of Pharmacy, Faculty of Medicine
来源：
Molecular Diagnosis & Therapy | 2017年 / 21卷
关键词：
Warfarin; Variant Allele; Warfarin Dose; Oral Clearance; CYP2C9 Genotype;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：75 / 83
页数：8
相关论文
共 50 条
  • [31] Frequency of CYP2C9 polymorphisms affecting warfarin metabolism in a large anticoagulant clinic cohort
    Moridani, Majid
    Fu, Lei
    Selby, Rita
    Yun, Francisco
    Sukovic, Tatjana
    Wong, Betty
    Cole, David E. C.
    [J]. CLINICAL BIOCHEMISTRY, 2006, 39 (06) : 606 - 612
  • [32] Effects of CYP2C9 polymorphisms on the pharmacokinetics of R- and S-phenprocournon in healthy volunteers
    Kirchheiner, J
    Ufer, M
    Walter, EC
    Kammerer, B
    Kahlich, R
    Meisel, C
    Schwab, M
    Gleiter, CH
    Rane, A
    Roots, I
    Brockmöller, J
    [J]. PHARMACOGENETICS, 2004, 14 (01): : 19 - 26
  • [33] Cytochrome P4502C9 polymorphisms (CYP2C9) and warfarin maintenance dose in elderly patients
    Siguret, V
    Gouin, I
    Golmard, JL
    Geoffroy, S
    Andreux, JP
    Pautas, E
    [J]. REVUE DE MEDECINE INTERNE, 2004, 25 (04): : 271 - 274
  • [34] Allele frequency distribution of CYP2C9*2 and CYP2C9*3 polymorphisms in six Mexican populations
    Castelan-Martinez, Osvaldo D.
    Hoyo-Vadillo, Carlos
    Sandoval-Garcia, Emmanuel
    Sandoval-Ramirez, Lucila
    Gonzalez-Ibarra, Miriam
    Solano-Solano, Gloria
    Gomez-Diaz, Rita A.
    Parra, Esteban J.
    Cruz, Miguel
    Valladares-Salgado, Adan
    [J]. GENE, 2013, 523 (02) : 167 - 172
  • [35] Distribution of polymorphisms in the CYP2C9 gene and CYP2C19/CYP2C9 haplotypes among Venezuelan populations
    Flores-Gutierrez, Sara
    Rodriguez-Larralde, Alvaro
    Vivenes de Lugo, Merlyn
    Castro de Guerra, Dinorah
    [J]. ANNALS OF HUMAN BIOLOGY, 2017, 44 (02) : 191 - 198
  • [36] CYP2C9 polymorphism: prevalence in healthy and warfarin-treated Malay and Chinese in Malaysia
    Ngow, H. A.
    Khairina, Wan W. M. N.
    Teh, L. K.
    Lee, W. L.
    Harun, R.
    Ismail, R.
    Salleh, M. Z.
    [J]. SINGAPORE MEDICAL JOURNAL, 2009, 50 (05) : 490 - 493
  • [37] Influence of CYP2C9 Polymorphisms on Plasma Concentration of Warfarin and 7-Hydroxy Warfarin in South Indian Patients
    Kumar, Dhakchinamoorthi Krishna
    Uppugunduri, Chakradhara Rao Satyanarayana
    Shewade, Deepak Gopal
    Chandran, Sai B., V
    Adithan, Chandrasekaran
    [J]. CURRENT DRUG METABOLISM, 2021, 22 (12) : 989 - 995
  • [38] CYP2C9 polymorphism and warfarin sensitivity in Taiwan Chinese
    Chern, HD
    Ueng, TH
    Fu, YP
    Cheng, CW
    [J]. CLINICA CHIMICA ACTA, 2006, 367 (1-2) : 108 - 113
  • [39] Prevalence of CYP2C9 polymorphisms in the south of Europe
    Sanchez-Diz, Paula
    Estany-Gestal, Ana
    Aguirre, Carmelo
    Blanco, Adoracion
    Carracedo, Angel
    Ibanez, Luisa
    Passiu, Marianna
    Provezza, Lisa
    Ramos-Ruiz, Ricardo
    Ruiz, Borja
    Salado-Valdivieso, Ines
    Velasco, Eladio A.
    Figueiras, Adolfo
    [J]. PHARMACOGENOMICS JOURNAL, 2009, 9 (05) : 306 - 310
  • [40] Association of Genetic Polymorphisms of CYP2C9 and VKORC1 with Bleeding Following Warfarin: A Case-Control Study
    Sridharan, Kannan
    Modi, Tanvi
    Bendkhale, Shital
    Kulkarni, Devranth
    Gogtay, Nithya J.
    Thatte, Urmila M.
    [J]. CURRENT CLINICAL PHARMACOLOGY, 2016, 11 (01): : 62 - 68
12345