Synergistic anti-tumor efficacy of doxorubicin and flavopiridol in an in vivo hepatocellular carcinoma model

被引:0
作者
Min-Sun Kwak
Su Jong Yu
Jung-Hwan Yoon
Sung-Hee Lee
Soo-Mi Lee
Jeong-Hoon Lee
Yoon Jun Kim
Hyo-Suk Lee
Chung Yong Kim
机构
[1] Seoul National University College of Medicine,Department of Internal Medicine and Liver Research Institute
[2] Seoul National University Hospital,Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center
来源
Journal of Cancer Research and Clinical Oncology | 2015年 / 141卷
关键词
Hepatocellular carcinoma; Doxorubicin; Flavopiridol; Apoptosis; Hypoxia;
D O I
暂无
中图分类号
学科分类号
摘要
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页码:2037 / 2045
页数:8
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[1]  
Akiba J(2008)N-myc downstream regulated gene 1 (NDRG1)/Cap43 enhances portal vein invasion and intrahepatic metastasis in human hepatocellular carcinoma Oncol Rep 20 1329-1335
[2]  
Ogasawara S(2012)Are there opportunities for chemotherapy in the treatment of hepatocellular cancer? J Hepatol 56 686-695
[3]  
Kawahara A(2012)Antitumor effect of vascular endothelial growth factor inhibitor sunitinib in preclinical models of hepatocellular carcinoma Eur J Gastroenterol Hepatol 24 563-574
[4]  
Nishida N(1984)Population pharmacokinetic data and parameter estimation based on their first two statistical moments Drug Metab Rev 15 173-193
[5]  
Sanada S(2009)Retinoblastoma tumor suppressor gene expression determines the response to sequential flavopiridol and doxorubicin treatment in small-cell lung carcinoma Clin Cancer Res 15 1232-1240
[6]  
Moriya F(2012)Improved chemotherapy for hepatocellular carcinoma Anticancer Res 32 1379-1386
[7]  
Kuwano M(2007)Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma Mod Pathol 20 76-83
[8]  
Nakashima O(2013)Endoplasmic reticulum stress-induced resistance to doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells PLoS ONE 8 e62627-S50
[9]  
Yano H(2004)Hepatocellular carcinoma in cirrhosis: incidence and risk factors Gastroenterology 127 S35-30380
[10]  
Asghar U(2001)Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2 J Biol Chem 276 30374-15