Rapid detection of hypoxia-inducible factor-1-active tumours: pretargeted imaging with a protein degrading in a mechanism similar to hypoxia-inducible factor-1α

被引:0
|
作者
Masashi Ueda
Takashi Kudo
Yuji Kuge
Takahiro Mukai
Shotaro Tanaka
Hiroaki Konishi
Azusa Miyano
Masahiro Ono
Shinae Kizaka-Kondoh
Masahiro Hiraoka
Hideo Saji
机构
[1] Kyoto University,Radioisotopes Research Laboratory, Kyoto University Hospital, Faculty of Medicine
[2] Kyoto University,Department of Patho
[3] Hokkaido University,Functional Bioanalysis, Graduate School of Pharmaceutical Sciences
[4] Kyushu University,Central Institute of Isotope Science
[5] Kyoto University,Department of Biomolecular Recognition Chemistry, Graduate School of Pharmaceutical Sciences
来源
European Journal of Nuclear Medicine and Molecular Imaging | 2010年 / 37卷
关键词
Tumour hypoxia; Hypoxia-inducible factor-1 (HIF-1); Oxygen-dependent degradation (ODD); Molecular imaging; Pretargeting;
D O I
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中图分类号
学科分类号
摘要
引用
收藏
页码:1566 / 1574
页数:8
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