A Novel Pure SERM Achieves Complete Regression of the Majority of Human Breast Cancer Tumors in Nude Mice

被引：0
|
作者：
Jenny Roy
Steeve Couillard
Mathieu Gutman
Fernand Labrie
机构：
[1] Laval University Medical Center (CHUL),Molecular Endocrinology and Oncology Research Center
[2] Laval University,undefined
来源：
Breast Cancer Research and Treatment | 2003年 / 81卷
关键词：
acolbifene; apoptosis; breast cancer; EM-652; pure antiestrogen; pure SERM (selective estrogen receptor modulator); SCH57068; tumorocidal; xenografts; ZR-75-1;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background. The objective was to determine if EM-652, a novel selective estrogen receptor modulator (SERM) having highly potent and pure antiestrogenic activity in the mammary gland could cause complete regression of the majority of human breast cancer xenografts in nude mice.
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页码：223 / 229
页数：6
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