Myosin Light Chain Kinase Inhibition: Correction of Increased Intestinal Epithelial Permeability In Vitro

被引:0
作者
Linda M. Feighery
Sean W. Cochrane
Teresa Quinn
Alan W. Baird
Daniel O’Toole
Sian-Eleri Owens
Diarmuid O’Donoghue
Randall J. Mrsny
David J. Brayden
机构
[1] University College Dublin,School of Agriculture, Food Science and Veterinary Medicine
[2] St. Vincent’s University Teaching Hospital,Welsh School of Pharmacy
[3] Cardiff University,undefined
来源
Pharmaceutical Research | 2008年 / 25卷
关键词
caco-2 monolayers; cytochalasins; dextran sodium sulphate; inflammatory bowel disease mouse models; mannitol fluxes; myosin light chain kinase; transepithelial electrical resistance;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1377 / 1386
页数:9
相关论文
共 184 条
[1]  
Cobrin G. M.(2005)Defects in mucosal immunity leading to Crohn’s disease Immunol. Rev. 206 277-295
[2]  
Abreu M. T.(2004)Increased intestinal permeability in patients with inflammatory bowel disease Eur. J. Med. Res. 9 456-460
[3]  
Welcker K.(1988)Effects of Infect Immun. 56 582-588
[4]  
Martin A.(2001) toxins A and B in rabbit small and large intestine Acta Physiol. Scand. 171 153-160
[5]  
Kolle P.(2005) and on cultured cells Lab. Invest 85 1308-1324
[6]  
Siebeck M.(1997)Effect of cholera toxin on passive transepithelial transport of Am. J. Physiol. 273 C1378-C1385
[7]  
Gross M.(2005)Cr-ethylenediaminetetraacetic acid and Am. J. Pathol. 166 409-419
[8]  
Lima A. A.(2006)C-mannitol in rat jejunum Am. J. Pathol. 169 1901-1909
[9]  
Lyerly Y. M.(2001)Enteropathogenic Am. J. Physiol. 281 G1487-G1493
[10]  
Wilkins T. D.(2006) disrupts tight junction barrier function and structure J. Cell Sci. 119 2095-2104