Mitochondrial DNA Mutations in Cardiovascular Diseases

被引：0
|
作者：
V. A. Korepanov
T. Y. Rebrova
R. E. Batalov
S. A. Afanasiev
机构：
[1] Cardiology Research Institute,
[2] Tomsk National Research Medical Center,undefined
[3] Russian Academy of Science,undefined
来源：
Russian Journal of Genetics | 2023年 / 59卷
关键词：
mitochondria; mutations; mitochondrial DNA; cardiovascular diseases;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Early prevention of the development and timely diagnosis of cardiovascular system diseases are some of the main problems in modern cardiology. One promising approach is to identify relationships between carriage of mitochondrial DNA (mtDNA) mutations and development of cardiovascular diseases. Mitochondria are the only source of energy accumulation in cardiomyocytes; therefore, failure of their functioning caused by mtDNA mutations directly affects the bioenergetics and work of myocardial cells. The objective of this review is to describe the current achievements in studying the relationships of mutant mtDNA with the development of various cardiovascular system diseases.
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页码：637 / 641
页数：4
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