Enhanced vanillin production from ferulic acid using adsorbent resin

被引：0
作者：
Dongliang Hua
Cuiqing Ma
Lifu Song
Shan Lin
Zhaobin Zhang
Zixin Deng
Ping Xu
机构：
[1] Shandong University,State Key Laboratory of Microbial Technology
[2] Shanghai Jiao Tong University,Key Laboratory of Microbial Metabolism, Ministry of Education, College of Life Science and Biotechnology
来源：
Applied Microbiology and Biotechnology | 2007年 / 74卷
关键词：
Vanillin; Ferulic acid; sp; Biotransformation; Adsorbent resin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
High vanillin productivity was achieved in the batch biotransformation of ferulic acid by Streptomyces sp. strain V-1. Due to the toxicity of vanillin and the product inhibition, fed-batch biotransformation with high concentration of ferulic acid was unsuccessful. To solve this problem and improve the vanillin yield, a biotransformation strategy using adsorbent resin was investigated. Several macroporous adsorbent resins were chosen to adsorb vanillin in situ during the bioconversion. Resin DM11 was found to be the best, which adsorbed the most vanillin and the least ferulic acid. When 8% resin DM11 (wet w/v) was added to the biotransformation system, 45 g l−1 ferulic acid could be added continually and 19.2 g l−1 vanillin was obtained within 55 h, which was the highest vanillin yield by bioconversion until now. This yield was remarkable for exceeding the crystallization concentration of vanillin and therefore had far-reaching consequence in its downstream processing.
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页码：783 / 790
页数：7
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