Iron status and neurobehavioral development of premature infants

被引：75

作者：

Armony-Sivan R. ^{[1
]}

Eidelman A.I. ^{[2
]}

Lanir A. ^{[3
]}

Sredni D. ^{[4
]}

Yehuda S. ^{[5
]}

机构：

[1] Department of Pediatrics, Shaare-Zedek Medical Center, Jerusalem

[2] Hebrew University School of Medicine, Jerusalem

[3] Biochemistry Department, Bnai-Zion Medical Center, Haifa

[4] Interdisciplinary Dept. of Soc. Sci., Bar-Ilan University, Ramat Gan

[5] Department of Psychology, Bar-Ilan University, Ramat Gan

来源：

Journal of Perinatology | 2004年 / 24卷 / 12期

关键词：

D O I：

10.1038/sj.jp.7211178

中图分类号：

学科分类号：

摘要：

Objective: This study was conducted to examine the relation between iron status and neurobehavioral development in premature infants. Study Design: Infants born before 34 weeks postmenstrual age and who were medically stable were studied. Anemia was defined as hemoglobin ≤ 10 g/Dl and low iron stores as a serum ferritin concentration ≤75 μ g/l. The infants were classified as anemic with low ferritin (Group 1; n = 18), anemic with normal ferritin (Group 2; n = 14), and nonanemic with normal ferritin (Group 3; n = 21). A total of 18 reflexes were behaviorally evaluated at 37 weeks postmenstrual age and "reflex scores" were compared between the groups. Higher scores reflect a greater percentage of abnormal reflexes. Results: Infants in group 1 (anemia/low ferritin) had a significantly higher reflex score (51.45±18.32%) than infants in Group 3 (38.32±17.7596). Group 2 had an intermediate score (45.40± 21.70%), but not different from the other two groups. Conclusion: These data indicate that low iron status, both measured by anemia and ferritin levels, is related to poorer neurobehavioral status in premature infants. © 2004 Nature Publishing Group All rights reserved.

引用

页码：757 / 762

页数：5

共 40 条

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