Irradiation induces DJ-1 secretion from esophageal squamous cell carcinoma cells to accelerate metastasis of bystander cells via a TGF-β1 positive feedback loop

被引:0
作者
Junjie Gu
Yuanyuan Sun
Jiahang Song
Ruiling Zhao
Xiaoke Di
Yumeng Zhang
Xiaolin Ge
Shu Zhang
Yun Gu
Xinchen Sun
机构
[1] Nanjing Medical University,The First School of Clinical Medicine
[2] The First Affiliated Hospital of Nanjing Medical University,Department of Radiation Oncology
[3] The First Affiliated Hospital of Nanjing Medical University,Department of Endocrinology
[4] The First Affiliated Hospital of Nanjing Medical University,Core Facility Center
[5] Lian Shui People’s Hospital,Department of Thoracic Surgery
来源
Journal of Experimental & Clinical Cancer Research | / 41卷
关键词
DJ-1; TGF-β1; HSC70; Smad3; TSP1; Esophageal squamous cell carcinoma; Radiation-induced bystander effect; Tumor metastasis;
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  • [1] Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
  • [2] Ferlay J(2015)Conditional Survival of Esophageal Cancer: An Analysis from the SEER Registry (1988–2011) J Thorac Oncol 10 1490-1497
  • [3] Soerjomataram I(2008)Irradiated fibroblast-induced bystander effects on invasive growth of squamous cell carcinoma under cancer-stromal cell interaction Cancer Sci 99 2417-2427
  • [4] Siegel RL(2021)Ionising Radiation Promotes Invasive Potential of Breast Cancer Cells: The Role of Exosomes in the Process Int J Mol Sci 22 11570-22231
  • [5] Torre LA(2021)Involvement of c-Myc in low dose radiation-induced senescence enhanced migration and invasion of unirradiated cancer cells Aging (Albany NY) 13 22208-946
  • [6] Jemal A(2020)Novel Insights into PARK7 (DJ-1), a Potential Anti-Cancer Therapeutic Target, and Implications for Cancer Progression J Clin Med 9 1256-372
  • [7] Kim E(2020)DJ-1 inhibits autophagy activity of prostate cancer cells by repressing JNK-Bcl2-Beclin1 signaling Cell Biol Int 44 937-3602
  • [8] Koroukian S(2021)Serum DJ-1 Is a biomarker of colorectal cancer and DJ-1 activates mitophagy to promote colorectal cancer progression Cancers (Basel). 13 4151-1128
  • [9] Thomas CR(2021)Knockdown of the DJ-1 (PARK7) gene sensitizes pancreatic cancer to erlotinib inhibition Mol Ther Oncolytics 20 364-616
  • [10] Kamochi N(2008)DJ-1 could predict worse prognosis in esophageal squamous cell carcinoma Cancer Epidemiol Biomarkers Prev 17 3593-960