Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis

[1] Aloe L(1992)Nerve growth factor in the synovial fluid of patients with chronic arthritis Arthritis Rheum 35 351-5

[2] Tuveri MA(2003)Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-alpha, interleukin-1 beta and cholecystokinin-8: the possible role of NGF in the inflammatory response Clin Exp Rheumatol 21 617-24

[3] Carcassi U(2007)Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis Osteoarthritis Cartilage 15 743-51

[4] Levi-Montalcini R(2010)Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis Rheumatology (Oxford) 49 1852-61

[5] Manni L(2010)Angiogenesis and the persistence of inflammation in a rat model of proliferative synovitis Arthritis Rheum 62 1890-8

[6] Lundeberg T(2011)Increased vascular penetration and nerve growth in the meniscus: a potential source of pain in osteoarthritis Ann Rheum Dis 70 523-9

[7] Fiorito S(2012)Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis Nat Rev Rheumatol 8 390-8

[8] Bonini S(2007)Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis Ann Rheum Dis 66 1423-8

[9] Vigneti E(2008)Angiogenesis in osteoarthritis Curr Opin Rheumatol 20 573-80

[10] Aloe L(2005)Osteoarthritis, angiogenesis and inflammation Rheumatology (Oxford) 44 7-16

[1] Aloe L(1992)Nerve growth factor in the synovial fluid of patients with chronic arthritis Arthritis Rheum 35 351-5

[2] Tuveri MA(2003)Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-alpha, interleukin-1 beta and cholecystokinin-8: the possible role of NGF in the inflammatory response Clin Exp Rheumatol 21 617-24

[3] Carcassi U(2007)Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis Osteoarthritis Cartilage 15 743-51

[4] Levi-Montalcini R(2010)Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis Rheumatology (Oxford) 49 1852-61

[5] Manni L(2010)Angiogenesis and the persistence of inflammation in a rat model of proliferative synovitis Arthritis Rheum 62 1890-8

[6] Lundeberg T(2011)Increased vascular penetration and nerve growth in the meniscus: a potential source of pain in osteoarthritis Ann Rheum Dis 70 523-9

[7] Fiorito S(2012)Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis Nat Rev Rheumatol 8 390-8

[8] Bonini S(2007)Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis Ann Rheum Dis 66 1423-8

[9] Vigneti E(2008)Angiogenesis in osteoarthritis Curr Opin Rheumatol 20 573-80

[10] Aloe L(2005)Osteoarthritis, angiogenesis and inflammation Rheumatology (Oxford) 44 7-16