Solid Organ Transplants in HIV-Infected Patients

被引：0
作者：
Jack Harbell
Norah A. Terrault
Peter Stock
机构：
[1] University of California San Francisco,Department of Surgery
[2] University of California San Francisco,Department of Medicine
[3] University of California San Francisco,Division of Gastroenterology
[4] University of California San Francisco,Department of Surgery
来源：
Current HIV/AIDS Reports | 2013年 / 10卷
关键词：
Liver transplantation; Kidney transplantation; HIV; AIDS; Liver failure; Renal failure; Hepatitis B; Hepatitis C; Immune suppression; Opportunistic infection; Graft survival; Patient survival; Selection criteria; Antiretroviral therapy; CD4+ T-cell count;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
There is a growing need for kidney and liver transplants in persons living with HIV. Fortunately, with the significant advances in antiretroviral therapy and management of opportunistic infections, HIV infection is no longer an absolute contraindication for solid organ transplantation. Data from several large prospective multi-center cohort studies have shown that solid organ transplantation in carefully selected HIV-infected individuals is safe. However, significant challenges have been identified including prevention of acute rejection, management of drug-drug interactions and treatment of recurrent viral hepatitis. This article reviews the selection criteria, outcomes, and special management considerations for HIV-infected patients undergoing liver or kidney transplantation.
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页码：217 / 225
页数：8
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