Sequential analysis applied to clinical trials in dentistry: A systematic review

被引：2

作者：

Bogowicz P. ^{[1
]}

Flores-Mir C. ^{[3
]}

Major P.W. ^{[2
]}

Heo G. ^{[3
]}

机构：

[1] Faculty of Science, Department of Mathematical and Statistical Sciences, Edmonton, AB

[2] Craniofacial and Oral-health Evidence-based Practice Group, Faculty of Medicine and Dentistry, Edmonton, AB

[3] Orthodontic Graduate Program, Faculty of Medicine and Dentistry, Edmonton, AB

来源：

Evidence-Based Dentistry | 2008年 / 9卷 / 2期

关键词：

D O I：

10.1038/sj.ebd.6400587

中图分类号：

学科分类号：

摘要：

Clinical trials employ sequential analysis for the ethical and economic benefits it brings. In dentistry, as in other fields, resources are scarce and efforts are made to ensure that patients are treated ethically. The objective of this systematic review was to characterise the use of sequential analysis for clinical trials in dentistry. We searched various databases from 1900 through to January 2008. Articles were selected for review if they were clinical trials in the field of dentistry that had applied some form of sequential analysis. Selection was carried out independently by two of the authors. We included 18 trials from various specialties, which involved many different interventions. We conclude that sequential analysis seems to be underused in this field but that there are sufficient methodological resources in place for future applications.

引用

页码：55 / 60

页数：5

共 42 条

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