Cariprazine alleviates core behavioral deficits in the prenatal valproic acid exposure model of autism spectrum disorder

被引:0
作者
Viktor Román
Nika Adham
Andrew G. Foley
Lynsey Hanratty
Bence Farkas
Balázs Lendvai
Béla Kiss
机构
[1] Gedeon Richter Plc,Berand Neuropharmacology Limited, NovaUCD, Belfield Innovation Park
[2] AbbVie,undefined
[3] University College Dublin,undefined
来源
Psychopharmacology | 2021年 / 238卷
关键词
Autism; Cariprazine; Risperidone; Aripiprazole; Core symptom; Social behavior; Repetitive behavior; Hyperactivity; Pharmacotherapy; Neurodevelopmental;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:2381 / 2392
页数:11
相关论文
共 473 条
  • [1] Amodeo DA(2014)Risperidone and the 5-HT2A receptor antagonist M100907 improve probabilistic reversal learning in BTBR T + tf/J mice Autism Res 7 555-567
  • [2] Jones JH(2014)Autistic-like syndrome in mu opioid receptor null mice is relieved by facilitated mGluR4 activity Neuropsychopharmacology 39 2049-2060
  • [3] Sweeney JA(2015)Lifetime development of behavioural phenotype in the house mouse (Mus musculus) Front Zool 12 S17-1287
  • [4] Ragozzino ME(2005)Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist J Pharmacol Exp Ther 315 1278-594
  • [5] Becker JA(2011)Fluoxetine but not risperidone increases sociability in the BTBR mouse model of autism Pharmacol Biochem Behav 97 586-2521
  • [6] Clesse D(2006)Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens J Neurosci 26 2513-277
  • [7] Spiegelhalter C(2014)Long-term effects of cariprazine exposure on dopamine receptor subtypes CNS Spectr 19 268-5860
  • [8] Schwab Y(2017)D3 receptors regulate excitability in a unique class of prefrontal pyramidal cells J Neurosci 37 5846-600
  • [9] Le Merrer J(2016)Variability of cortical oscillation patterns: a possible endophenotype in autism spectrum disorders? Neurosci Biobehav Rev 71 590-1103
  • [10] Kieffer BL(2011)Dopamine D3-like receptors modulate anxiety-like behavior and regulate GABAergic transmission in the rat lateral/basolateral amygdala Neuropsychopharmacology 36 1090-1582