Sentinel lymph node biopsy in breast cancer [Sentinel lymph node beim mammakarzinom]

被引：0
作者：
Rody A. [1 ]
Solbach C. [1 ]
Kaufmann M. [1 ,2 ]
机构：
[1] Klinik für Gynäkologie und Geburtshilfe, Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt/Main
[2] Klinik für Gynäkologie und Geburtshilfe, Klinikum der Johann Wolfgang Goethe-Universität, 60590 Frankfurt/Main
来源：
Der Chirurg | 2004年 / 75卷 / 8期
关键词：
Breast cancer; Extramammary lymph nodes; Micrometastases; Primary chemotherapy; Sentinel node;
D O I：
10.1007/s00104-004-0897-6
中图分类号：
学科分类号：
摘要：
Surgical treatment of breast cancer has changed dramatically during the last few decades with the aim of reducing surgical radicality in the breast and also in the axilla. In this context sentinel node biopsy is a reliable technique to determine axillary node status of breast cancer patients and reduce morbidity associated with standard axillary lymph node dissection. Although SNB is performed with increasing frequency, an incorrect indication and lack of experience with the surgical procedure can minimize the sensitivity and specificity of this method. In consequence, this could lead to wrong tumor staging and inappropriate adjuvant therapy. Therefore, we describe the basic requirements, indications, and pitfalls of this technique. Since many issues are controversial such as the prognostic value of micrometastases and extramammary nodes as well as the use of SNB after primary chemotherapy and in ductal carcinoma in situ, further clinical studies are necessary. © Springer-Verlag 2004.
引用
收藏
页码：767 / 773
页数：6
相关论文
共 40 条
  • [1] Allweis T.M., Badriyyah M., Bar Ad V., Et al., Current controversies in sentinel lymph node biopsy for breast cancer, Breast, 12, pp. 163-171, (2003)
  • [2] Berg J.W., The significance of axillary node levels in the study of breast carcinoma, Cancer, 8, pp. 776-778, (1955)
  • [3] Borgstein P.J., Pijpers R., Comans E.F., Et al., Sentinel lymph node biopsy in breast cancer: Guidelines and pitfalls of lymphoscintigraphy and gamma probe detection, J Am Coll Surg, 186, pp. 275-283, (1998)
  • [4] Chung M.A., Steinhoff M.M., Cady B., Clinical axillary recurrence in breast cancer patients after a negative sentinel node biopsy, Am J Surg, 184, pp. 310-314, (2002)
  • [5] Cote R.J., Peterson H.F., Chaiwun B., Et al., Role of immunohistochemical detection of lymph-node metastases in management of breast cancer, Lancet, 354, pp. 896-900, (1999)
  • [6] Cox C.E., Pendas S., Cox J.M., Et al., Guidelines for sentinel node biopsy and lymphatic mapping of patients with breast cancer, Ann Surg, 227, pp. 645-651, (1998)
  • [7] Cox C.E., Nguyen K., Gray R.J., Et al., Importance of lymphatic mapping in ductal carcinoma in situ (DCIS): Why map DCIS?, Am Surg, 67, pp. 513-519, (2001)
  • [8] De Cicco C., Cremonesi M., Luini A., Et al., Lymphoscintigraphy and radioguided biopsy of the sentinel axillary node in breast cancer, Eur J Nucl Med, 39, pp. 2080-2084, (1998)
  • [9] Dupont E.L., Salud C.J., Peltz E.S., Et al., Clinical relevance of internal mammary node mapping as a guide to radiation therapy, Am J Surg, 182, pp. 321-324, (2001)
  • [10] Edge S.B., Niland J.C., Bookman M.A., Et al., Emergence of sentinel node biopsy in breast cancer as standard-of-care in academic comprehensive cancer centers, J Natl Cancer Inst, 95, pp. 1514-1521, (2003)
1234