Expression of PD-1/PD-L1 axis in mediastinal lymph nodes and lung tissue of human and experimental lung fibrosis indicates a potential therapeutic target for idiopathic pulmonary fibrosis

被引：0

作者：

Theodoros Karampitsakos

Apostolos Galaris

Serafeim Chrysikos

Ourania Papaioannou

Ioannis Vamvakaris

Ilianna Barbayianni

Paraskevi Kanellopoulou

Sofia Grammenoudi

Nektarios Anagnostopoulos

Grigoris Stratakos

Matthaios Katsaras

Fotios Sampsonas

Katerina Dimakou

Effrosyni D. Manali

Spyridon Papiris

Bochra Tourki

Brenda M Juan-Guardela

Petros Bakakos

Demosthenes Bouros

Jose D Herazo-Maya

Vassilis Aidinis

Argyris Tzouvelekis

机构：

[1] University Hospital of Patras,Department of Respiratory Medicine

[2] University of South Florida,Ubben Center and Laboratory for Pulmonary Fibrosis Research, Morsani College of Medicine

[3] Institute of Bio- Innovation,5th Department of Pneumonology

[4] Biomedical Sciences Research Center Alexander Fleming,Department of Pathology

[5] Hospital for Thoracic Diseases,First Academic Department of Pneumonology, “SOTIRIA”, Medical School

[6] “SOTIRIA”,2nd Pulmonary Medicine Department, Athens Medical School

[7] Hospital for Thoracic Diseases,undefined

[8] “SOTIRIA”,undefined

[9] Hospital for Thoracic Diseases,undefined

[10] National and Kapodistrian University of Athens,undefined

[11] “ATTIKON” University Hospital,undefined

[12] National and Kapodistrian University of Athens,undefined

来源：

Respiratory Research | / 24卷

关键词：

Idiopathic pulmonary fibrosis; Mediastinal lymph nodes; Lung cancer; PD-1/PD-L1 axis; Pembrolizumab;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 50 条

[21] Clinical Significance of PD-L1 Status and the Expression of PD-1 in Tumor-Infiltrating Lymphocytes (TILs) in Lung Cancer
Ortiz-Villalon, Cristian
Karagkounis, Georgios
Kis, Lorand
Lewensohn, Rolf
Rassidakis, Georgios
Tendler, Salomon
De Petris, Luigi
[J]. JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S1514 - S1514
[22] Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors
Dart, Sarah J.
Cook, Alistair M.
Millward, Michael J.
McDonnell, Alison M.
Chin, Wee L.
Hakeem, Muhammad U.
Meniawy, Tarek M.
Bowyer, Samantha E.
[J]. SCIENTIFIC REPORTS, 2021, 11 (01)
[23] Companion and Complementary Diagnostics-Focus on PD-L1 Expression Assays for PD-1/PD-L1 Checkpoint Inhibitors in Non-Small Cell Lung Cancer
Hersom, Maria
Jorgensen, Jan T.
[J]. THERAPEUTIC DRUG MONITORING, 2018, 40 (01) : 9 - 16
[24] A Mesoporous Gold Sensor Unveils Phospho PD-L1 in Extracellular Vesicles as a Proxy for PD-L1 Expression in Lung Cancer Tissue
Shanmugasundaram, Karthik B.
Ahmed, Emtiaz
Miao, Xinzhe
Kulasinghe, Arutha
Fletcher, James A.
Monkman, James
Mainwaring, Paul
Masud, Mostafa Kamal
Park, Hyeongyu
Hossain, Md Shahriar A.
Yamauchi, Yusuke
Sina, Abu A. I.
O'Byrne, Kenneth
Wuethrich, Alain
Trau, Matt
[J]. ACS SENSORS, 2024, 9 (06): : 3009 - 3016
[25] Expression of PD-1 and Its Ligands, PD-L1 and PD-L2, in Smokers and Never Smokers with KRAS-Mutant Lung Cancer
Calles, Antonio
Liao, Xiaoyun
Sholl, Lynette M.
Rodig, Scott J.
Freeman, Gordon J.
Butaney, Mohit
Lydon, Christine
Dahlberg, Suzanne E.
Hodi, F. Stephen
Oxnard, Geoffrey R.
Jackman, David M.
Jaenne, Pasi A.
[J]. JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (12) : 1726 - 1735
[26] PD-1/PD-L1 Inhibitors as Monotherapy in the First-Line Treatment of Advanced Non-Small Cell Lung Cancer Patients with High PD-L1 Expression: An Expert Position Statement
Isla, Dolores
Sanchez, Alfredo
Casal, Joaquin
Cobo, Manuel
Majem, Margarita
Reguart, Noemi
Zugazagoitia, Jon
Bernabe, Reyes
[J]. JOURNAL OF CLINICAL MEDICINE, 2023, 12 (15)
[27] PD-L1 expression and EGFR status in advanced non-small-cell lung cancer patients receiving PD-1/PD-L1 inhibitors: a meta-analysis
Li, Jing
Gu, Jian
[J]. FUTURE ONCOLOGY, 2019, 15 (14) : 1667 - 1678
[28] PD-1/PD-L1 inhibitors in treatment-naive, advanced non-small cell lung cancer patients with < 1% PD-L1 expression: a meta-analysis of randomized controlled trials
Wankhede, Durgesh
Hofman, Paul
Grover, Sandeep
[J]. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023, 149 (05) : 2179 - 2189
[29] Current Clinical Progress of PD-1/PD-L1 Immunotherapy and Potential Combination Treatment in Non-Small Cell Lung Cancer
Li, Jia-Xin
Huang, Ju-Min
Jiang, Ze-Bo
Li, Run-Ze
Sun, Ao
Leung, Elaine Lai-Han
Yan, Pei-Yu
[J]. INTEGRATIVE CANCER THERAPIES, 2019, 18
[30] Expression of PD-1/PD-L1 and PD-L2 in peripheral T-cells from non-small cell lung cancer patients
Arrieta, Oscar
Montes-Servin, Edgar
Hernandez-Martinez, Juan-Manuel
Cardona, Andres F.
Casas-Ruiz, Eibar
Crispin, Jose C.
Motola, Daniel
Flores-Estrada, Diana
Barrera, Lourdes
[J]. ONCOTARGET, 2017, 8 (60) : 101994 - 102005

← 1 2 3 4 5 →