A case of pancreatic solid-pseudopapillary neoplasm with marked ossification

被引:3
作者
Tajima K. [1 ]
Kawaguchi Y. [1 ]
Ito H. [1 ]
Ogawa M. [1 ]
Toriumi K. [2 ]
Hirabayashi K. [2 ]
Takekoshi S. [2 ]
Mine T. [1 ]
机构
[1] Department of Gastroenterology, Tokai University, School of Medicine, Isehara, Kanagawa 259-1193
[2] Department of Pathology, Tokai University, School of Medicine, Isehara, Kanagawa 259-1193
关键词
Ossification; Pancreas; Solid-pseudopapillary neoplasm;
D O I
10.1007/s12328-011-0202-4
中图分类号
学科分类号
摘要
A cystic lesion of the pancreas was detected in a 25-year-old asymptomatic woman during a company medical checkup. Abdominal computed tomography (CT) revealed an ossified lesion in the pancreatic body, and the patient was referred to us for further management. Abdominal ultrasound and endoscopic ultrasound showed a hypoechoic mass with a large ossific focus, measuring 25 mm in the pancreatic body. CT and magnetic resonance imaging (MRI) showed a nonenhancing tumor lesion with a large calcific focus, measuring 20 mm in the pancreatic body. Endoscopic retrograde pancreatography revealed mild stenosis of the main pancreatic duct near the ossific focus in the pancreatic body. From the above, a pancreatic solid-pseudopapillary neoplasm (SPN) was suspected, and resection of the pancreatic body was performed. Intraoperatively, a whitish tumor measuring about 20 mm was recognized. Histopathologically, moderately large-sized tumor cells containing eosinophilic cytoplasm were arranged in a pseudopapillary formation, and infiltrated the surrounding normal tissue with ossification. Immunostaining was positive for α1-antitrypsin, not inconsistent with the diagnosis of SPN. We report this case of pancreatic SPN with ossification and a review of the literature. © 2011 Springer.
引用
收藏
页码:112 / 117
页数:5
相关论文
共 16 条
[1]  
Frantz V.K., Tumor of the pancreas, Atlas of Tumor Pathology VII, pp. 32-33, (1959)
[2]  
Kloeppel G., Morohoschi T., John H.D., Solid and cystic acinar cell tumor of the pancreas. A tumor in young women with favorable prognosis, Virchows Archiv - Abteilung A Pathologische Anatomie, 392, 2, pp. 171-183, (1981)
[3]  
Yoshioka M., Egami I., Maeda S., Katayama H., Matsuda K., Uchida E., Et al., Clinicopathological feature and surgical treatment of solid-pseudopapillary tumor of the pancreas-a review of 302 cases reported in Japan and our six cases (in Japanese with English abstract), Tan sui, 22, pp. 45-52, (2001)
[4]  
Nakagawa N., Murakami Y., Uemura K., Hayashidani Y., Sudo T., Hashimoto Y., Et al., Eight cases of solid-pseudopapillary tumors (SPT) of the pancreas (in Japanese with English abstract), Suizo, 23, pp. 132-139, (2008)
[5]  
Kimura W., Moriya T., Clinical features and therapeutical strategies for solid-pseudopapillary tumor of the pancreas (in Japanese with English abstract), Kan Tan sui, 44, pp. 25-32, (2002)
[6]  
Iijima T., Nitta A., Horiuchi H., Sumi Y., Tamamoto F., Fukunaga M., Et al., A case of solid and cystic tumor of the pancreas with ossification-Follow-up study of the 45 cases in Japan- (in Japanese with English abstract), Nippon Shokakibyo Gakkai Zasshi, 85, pp. 1123-1127, (1988)
[7]  
Uchimi K., Fujita N., Noda Y., Kobayashi G., Kimura K., Matsunaga A., Yuki T., Nomura M., Sato T., Ishida K., Seno S., Ito K., Okubo K., Suzuki T., Hirasawa D., Sugawara T., Horaguchi J., Tada T., Takazawa O., Solid cystic tumor of the pancreas: Report of six cases and a review of the Japanese literature, Journal of Gastroenterology, 37, 11, pp. 972-980, (2002)
[8]  
Matsunou H., Konishi F., Yamamichi N., Takayanagi N., Mukai M., Solid, infiltrating variety of papillary cystic neoplasm of the pancreas, Cancer, 65, 12, pp. 2747-2757, (1990)
[9]  
Takeuchi M., Yamagami K., Kuno F., A case of solid cystic tumor of the pancreas with ossification and infiltrative growth, Jpn J Cancer Clin, 43, pp. 947-951, (1997)
[10]  
Nakamura S., Okayama Y., Imai H., Aoki S., Kobayashi S., Hattori T., Shiraki S., Goto K., Sano H., Ohara H., Nomura T., Joh T., Yoshifumi Y., Itoh M., A solid cystic tumor of the pancreas with ossification and possible malignancy, coexisting nonfusion of the pancreatic ducts, Journal of Clinical Gastroenterology, 33, 4, pp. 333-336, (2001)