Electron cryo-microscopy structure of the mechanotransduction channel NOMPC

被引：0

作者：

Peng Jin

David Bulkley

Yanmeng Guo

Wei Zhang

Zhenhao Guo

Walter Huynh

Shenping Wu

Shan Meltzer

Tong Cheng

Lily Yeh Jan

Yuh-Nung Jan

Yifan Cheng

机构：

[1] University of California,Department of Physiology

[2] University of California,Department of Biochemistry and Biophysics

[3] Howard Hughes Medical Institute,Department of Cellular and Molecular Pharmacology

[4] University of California,undefined

[5] University of California,undefined

来源：

Nature | 2017年 / 547卷

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D O I：

暂无

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学科分类号：

摘要：

Single-particle electron cryo-microscopy analysis of the mechanotransduction channel NOMPC reveals that it contains a bundle of four helical spring-shaped ankyrin repeat domains that undergo motion, potentially allowing mechanical movement of the cytoskeleton to be coupled to the opening of the channel.

引用

页码：118 / 122

页数：4

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