Genetics of body-weight regulation

被引：0
作者：
Gregory S. Barsh
I. Sadaf Farooqi
Stephen O'Rahilly
机构：
[1] Beckman Center,Departments of Pediatrics and Genetics and the Howard Hughes Medical Institute
[2] University of Cambridge,Departments of Medicine and Clinical Biochemistry
[3] Addenbrooke's Hospital,undefined
来源：
Nature | 2000年 / 404卷
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学科分类号：
摘要：
The role of genetics in obesity is twofold. Studying rare mutations in humans and model organisms provides fundamental insight into a complex physiological process, and complements population-based studies that seek to reveal primary causes. Remarkable progress has been made on both fronts, and the pace of advance is likely to accelerate as functional genomics and the human genome project expand and mature. Approaches based on mendelian and quantitative genetics may well converge, and lead ultimately to more rational and selective therapies.
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页码：644 / 651
页数：7
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