APE1 promotes non-homologous end joining by initiating DNA double-strand break formation and decreasing ubiquitination of artemis following oxidative genotoxic stress

[1] Schaue D(2015)Opportunities and challenges of radiotherapy for treating cancer Nat Rev Clin Oncol 12 527-540

[2] McBride WH(2021)Early events in radiobiology: isolated and cluster DNA damage induced by initial cations and nonionizing secondary electrons J Phys Chem Lett 12 717-723

[3] Dong Y(2011)Unrepaired clustered DNA lesions induce chromosome breakage in human cells Proc Natl Acad Sci 108 8293-8298

[4] Liao H(2015)Biomolecular damage induced by ionizing radiation: the direct and indirect effects of low-energy electrons on DNA Annu Rev Phys Chem 66 379-398

[5] Gao Y(2019)Ionizing radiation and complex DNA damage: from prediction to detection challenges and biological significance Cancers 11 1789-13

[6] Cloutier P(2020)Mammalian DNA base excision repair: dancing in the moonlight DNA Repair 93 102921-8923

[7] Zheng Y(2012)Overview of base excision repair biochemistry Curr Mol Pharmacol 5 3-100

[8] Sanche L(1996)The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice Proc Natl Acad Sci 93 8919-228

[9] Asaithamby A(2018)APE1: a skilled nucleic acid surgeon DNA Repair 71 93-96

[10] Hu B(2021)The multifunctional APE1 DNA repair–redox signaling protein as a drug target in human disease Drug Discov Today 26 218-709

[1] Schaue D(2015)Opportunities and challenges of radiotherapy for treating cancer Nat Rev Clin Oncol 12 527-540

[2] McBride WH(2021)Early events in radiobiology: isolated and cluster DNA damage induced by initial cations and nonionizing secondary electrons J Phys Chem Lett 12 717-723

[3] Dong Y(2011)Unrepaired clustered DNA lesions induce chromosome breakage in human cells Proc Natl Acad Sci 108 8293-8298

[4] Liao H(2015)Biomolecular damage induced by ionizing radiation: the direct and indirect effects of low-energy electrons on DNA Annu Rev Phys Chem 66 379-398

[5] Gao Y(2019)Ionizing radiation and complex DNA damage: from prediction to detection challenges and biological significance Cancers 11 1789-13

[6] Cloutier P(2020)Mammalian DNA base excision repair: dancing in the moonlight DNA Repair 93 102921-8923

[7] Zheng Y(2012)Overview of base excision repair biochemistry Curr Mol Pharmacol 5 3-100

[8] Sanche L(1996)The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice Proc Natl Acad Sci 93 8919-228

[9] Asaithamby A(2018)APE1: a skilled nucleic acid surgeon DNA Repair 71 93-96

[10] Hu B(2021)The multifunctional APE1 DNA repair–redox signaling protein as a drug target in human disease Drug Discov Today 26 218-709