Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function

被引：0
作者：
Xiaoyu He
Qiaohong Lai
Cai Chen
Na Li
Fei Sun
Wenting Huang
Shu Zhang
Qilin Yu
Ping Yang
Fei Xiong
Zhishui Chen
Quan Gong
Boxu Ren
Jianping Weng
Décio L. Eizirik
Zhiguang Zhou
Cong-Yi Wang
机构：
[1] Huazhong University of Science and Technology,The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education and Ministry of Health, Tongji Hospital, Tongji Medical College
[2] Medical College of Yangtze University,Department of Endocrinology and Metabolism, The Third Affiliated Hospital
[3] Sun Yat-Sen University,Diabetes Center, The Second Xiangya Hospital, Institute of Metabolism and Endocrinology
[4] ULB Center for Diabetes Research,undefined
[5] Université Libre de Bruxelles,undefined
[6] Central South University,undefined
来源：
Diabetologia | 2018年 / 61卷
关键词：
Diabetes; Insulin content; Insulin secretion; NRF2; Oxidative stress; Pancreatic beta cell; SUMOylation; UBC9;
D O I：
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摘要：
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页码：881 / 895
页数：14
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