Seom guidelines for the treatment of gastric cancer 2015

被引:0
作者
M. Martin-Richard
A. Custodio
C. García-Girón
C. Grávalos
C. Gomez
P. Jimenez-Fonseca
J. L. Manzano
C. Pericay
F. Rivera
A. Carrato
机构
[1] Hospital de la Santa Creu I Sant Pau,Medical Oncology Department
[2] Hospital Universitario Clínico San Carlos,Medical Oncology Department
[3] Hospital Universitario de Burgos,Medical Oncology Department
[4] Hospital Universitario 12 de Octubre,Medical Oncology Department
[5] Hospital Universitario Central de Asturias (HUCA),Medical Oncology Department
[6] Hospital Universitari Germans Trias I Pujol de Badalona,Medical Oncology Department
[7] Hospital de Sabadell-Consorcio Sanitario Parc Taulì,Medical Oncology Department
[8] Hospital Universitario Marqués de Valdecilla,Medical Oncology Department
[9] Hospital Universitario Ramón y Cajal,Medical Oncology Department
来源
Clinical and Translational Oncology | 2015年 / 17卷
关键词
Gastric adenocarcinoma; Cardia; Diagnosis; Treatment; Clinical guidelines;
D O I
暂无
中图分类号
学科分类号
摘要
Gastric cancer is the fourth cause of death by cancer in Spain and a significant medical problem. Molecular biology results evidence that gastroesophageal junction tumors and gastric cancer should be considered as two independent entities with a different prognosis and treatment approach. Endoscopic resection in very early tumors is feasible. Neoadjuvant and adjuvant therapy in locally advanced resectable tumor increase overall survival and should be considered standard treatments. In stage IV tumors, platinum–fluoropyrimidine-based schedule, with trastuzumab in HER2-overexpressed tumors, is the first-line treatment. Different therapies in second line have demonstrated in randomized studies their clear benefit in survival improvement.
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页码:996 / 1004
页数:8
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