High-density lipoprotein apolipoprotein A-I kinetics in obese insulin resistant patients. An in vivo stable isotope study

被引:0
作者
F Pont
L Duvillard
E Florentin
P Gambert
B Vergès
机构
[1] Laboratoire de Biochimie des Lipoprotéines,
[2] INSERM U 498,undefined
[3] Faculté de Médecine,undefined
[4] Service Endocrinologie,undefined
[5] Diabétologie et Maladies Métaboliques,undefined
[6] Centre Hospitalier Universitaire de Dijon,undefined
来源
International Journal of Obesity | 2002年 / 26卷
关键词
insulin resistance; HDL; kinetic; stable isotope; lipid; apolipoprotein A-I; insulin;
D O I
暂无
中图分类号
学科分类号
摘要
AIMS/HYPOTHESIS: Mechanisms responsible for the decreased high-density lipoprotein (HDL) cholesterol level associated with insulin resistance in obese patients are not clearly understood. To determine the influence of insulin resistance at an early stage on HDL metabolism, we performed a stable isotope kinetic study of apolipoprotein (apo) A-I, in five obese insulin resistant women with normal fasting triglycerides and without impaired glucose tolerance, and in five age-matched control women.
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页码:1151 / 1158
页数:7
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