Biochemical Markers of Bone Turnover in the Clinical Development of Drugs for Osteoporosis and Metastatic Bone DiseasePotential Uses and Pitfalls

被引：0
|
作者：
Serge Cremers
Patrick Garnero
机构：
[1] Columbia University,Department of Medicine, Endocrinology
[2] Leiden University Medical Center,Department of Clinical Pharmacy and Toxicology
[3] Inserm Research Unit,undefined
[4] Molecular Markers,undefined
[5] Synarc,undefined
来源：
Drugs | 2006年 / 66卷
关键词：
Bone Mineral Density; Osteoporosis; Bone Metastasis; Bisphosphonates; Bone Turnover;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Biochemical markers of bone turnover are used increasingly during the clinical development of drugs for the treatment of metabolic bone diseases such as Paget’s disease, osteoporosis and cancer that has metastasised to the bone. However, assessing the optimal value of these markers is often complicated, and such an assessment is an obvious prerequisite for rational use of the markers and, consequently, potential improvement of clinical drug development.
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页码：2031 / 2058
页数：27
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