Are native proteins metastable?

被引：0

作者：

D. Thirumalai

G. Reddy

机构：

[1] D. Thirumalai and G. Reddy are in the Institute for Physical Science and Technology,

[2] University of Maryland,undefined

[3] College Park,undefined

[4] Maryland 20742,undefined

[5] USA,undefined

来源：

Nature Chemistry | 2011年 / 3卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Thermodynamic measurements show that the most stable structural form of a number of proteins under cellular conditions is fibrillar, implying that their functional states may only be metastable.

引用

页码：910 / 911

页数：1

共 16 条

[1]

Baldwin AJ(2011)undefined J. Am. Chem. Soc. 133 14160-14163

[2]

Kodali R(2007)undefined Curr. Opin. Struct. Biol. 17 48-57

[3]

Wetzel R(1962)undefined J. Mol. Biol. 4 10-21

[4]

Oosawa F(1990)undefined Proc. Natl Acad. Sci. 87 3526-3529

[5]

Kasai M(1998)undefined Nature Struct. Biol. 5 236-241

[6]

Honeycutt JD(2003)undefined Curr. Opin. Struct. Biol. 13 146-159

[7]

Thirumalai D(2008)undefined Science 319 916-919

[8]

Dinner AR(undefined)undefined undefined undefined undefined-undefined

[9]

Karplus M(undefined)undefined undefined undefined undefined-undefined

[10]

Thirumalai D(undefined)undefined undefined undefined undefined-undefined

← 1 2 →