Evaluation of the novel liver micronucleus assay using formalin-fixed tissues

[1] Hamada S(2015)Evaluation of the repeated-dose liver and gastrointestinal tract micronucleus assays with 22 chemicals using young adult rats: summary of the collaborative study by the collaborative study Group for the Micronucleus Test (CSGMT)/The Japanese environmental mutagen society (JEMS) - mammalian mutagenicity study group (MMS) Mutat Res 780-781 2-17

[2] Ohyama W(1976)Cytogenetic effects of mutagens/carcinogens after activation in a microsomal system in vitro I. induction of chromosome aberrations and sister chromatid exchanges by diethylnitrosamine (DEN) and dimethylnitrosamine (DMN) in CHO cells in the presence of rat-liver microsomes Mutat Res 37 83-90

[3] Takashima R(1991)Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U. S. NTP Mutat Res 257 229-306

[4] Shimada K(1997)Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (group 1, 2A and 2B). The summary report of the 6th collaborative study by CSGMT/JEMS∙MMS Mutat Res 389 3-122

[5] Matsumoto K(1991)Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene using the rat micronucleus test and rat liver UDS assay Carcinogenesis. 12 2233-2237

[6] Kawakami S(1980)A micronucleus technique for detecting clastogenic effects of mutagens/carcinogens (DEN, DMN) in hepatocytes of rat liver in vivo Mutat Res 74 11-20

[7] Uno F(1989)The role of short-lived lesions in the induction of micronuclei in rat liver by ethylnitrosourea and methyl methanesulfonate: the importance of experimental design Mutat Res 210 271-279

[8] Sui H(1995)Tissues other than bone marrow that can be used for cytogenetic analysis Environ Mol Mutagen 25 338-343

[9] Shimada Y(1988)A non-invasive micronucleus assay in the rat liver Mutat Res 203 23-32

[10] Imamura T(1989)The rat-liver carcinogen N-nitrosomorpholine initiates unscheduled DNA synthesis and induces micronuclei in the rat liver in vivo Mutat Res 225 143-147

[1] Hamada S(2015)Evaluation of the repeated-dose liver and gastrointestinal tract micronucleus assays with 22 chemicals using young adult rats: summary of the collaborative study by the collaborative study Group for the Micronucleus Test (CSGMT)/The Japanese environmental mutagen society (JEMS) - mammalian mutagenicity study group (MMS) Mutat Res 780-781 2-17

[2] Ohyama W(1976)Cytogenetic effects of mutagens/carcinogens after activation in a microsomal system in vitro I. induction of chromosome aberrations and sister chromatid exchanges by diethylnitrosamine (DEN) and dimethylnitrosamine (DMN) in CHO cells in the presence of rat-liver microsomes Mutat Res 37 83-90

[3] Takashima R(1991)Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U. S. NTP Mutat Res 257 229-306

[4] Shimada K(1997)Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (group 1, 2A and 2B). The summary report of the 6th collaborative study by CSGMT/JEMS∙MMS Mutat Res 389 3-122

[5] Matsumoto K(1991)Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene using the rat micronucleus test and rat liver UDS assay Carcinogenesis. 12 2233-2237

[6] Kawakami S(1980)A micronucleus technique for detecting clastogenic effects of mutagens/carcinogens (DEN, DMN) in hepatocytes of rat liver in vivo Mutat Res 74 11-20

[7] Uno F(1989)The role of short-lived lesions in the induction of micronuclei in rat liver by ethylnitrosourea and methyl methanesulfonate: the importance of experimental design Mutat Res 210 271-279

[8] Sui H(1995)Tissues other than bone marrow that can be used for cytogenetic analysis Environ Mol Mutagen 25 338-343

[9] Shimada Y(1988)A non-invasive micronucleus assay in the rat liver Mutat Res 203 23-32

[10] Imamura T(1989)The rat-liver carcinogen N-nitrosomorpholine initiates unscheduled DNA synthesis and induces micronuclei in the rat liver in vivo Mutat Res 225 143-147