Update on progressive supranuclear palsy

被引:42
作者
Litvan I. [1 ]
机构
[1] Movement Disorder Program, Department of Neurology, Univ. of Louisville Sch. of Medicine, Louisville, KY 40202, A Building
关键词
Multiple System Atrophy; Dementia With Lewy Body; Progressive Supranuclear Palsy; Corticobasal Degeneration; Parkinsonian Disorder;
D O I
10.1007/s11910-004-0055-z
中图分类号
学科分类号
摘要
A better understanding of the challenges in the diagnosis of progressive supranuclear palsy (PSP), the most common atypical parkinsonian neurodegenerative disorder, has led to improving its diagnostic accuracy. Similarly, a better understanding of the role of tau mutations, mitochondrial complex I inhibitors, oxidative injury, and inflammation in neurodegeneration has led to an unraveling of potential risk factors for the development of PSP. These advances are explained in detail in this review. Copyright © 2004 by Current Science Inc.
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页码:296 / 302
页数:6
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