Autophagy induced by a sulphamoylated estrone analogue contributes to its cytotoxic effect on breast cancer cells

被引:0
作者
Marcel Verwey
Elsie M. Nolte
Anna M. Joubert
Anne E. Theron
机构
[1] University of Pretoria,Department of Physiology, Faculty of Health Sciences
来源
Cancer Cell International | / 16卷
关键词
Breast cancer; Autophagy; Apoptosis; Cell survival; ESE-15-ol; 3-Methyladenine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 191 条
[1]  
Lewis J(2005)Differential effects of 16α-hydroxyestrone and 2-methoxyestradiol on cyclin d1 involving the transcription factor atf-2 in mcf-7 breast cancer cells J Mol Endocrinol 34 94-105
[2]  
Thomas T(1960)Oxidative metabolism of estradiol J Biol Chem 235 3104-3107
[3]  
Pestell R(2004)Induction of apoptosis and G2/m arrest by 2-methoxyestradiol in human cervical cancer HeLaS3 cells Anticancer Res 24 873-880
[4]  
Fishman J(2006)2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro sar, protein crystallography, and in vivo activity J Med Chem 49 7683-7696
[5]  
Bradlow H(2010)In vitro effects of 2-methoxyestradiol on morphology, cell cycle progression, cell death and gene expression changes in tumorigenic mcf-7 breast epithelial cell line J Steroid Biochem Mol Biol 119 149-160
[6]  
Gallagher T(2013)Sulphamoylated 2-methoxyestradial analogues induce apoptosis in adenocarcinoma cell lines PLoS ONE 8 e71935-1520
[7]  
Li L(2004)2-Methoxyestradiol induces cell cycle arrest and apoptosis of nasopharyngeal carcinoma cells Acta Pharmacol Sin 25 1515-2585
[8]  
Bu S(2012)In vitro evaluation of ese-15-ol, an estradiol analogue with nanomolar antimitotic and carbonic anhydrase inhibitory activity PLoS ONE 7 e52205-437
[9]  
Bäckström T(2009)How do anti-mitotic drugs kill cancer cells? J Cell Sci 122 2579-403
[10]  
Landström M(2014)Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations Cancer Chemother Pharmacol 75 431-228