L-Histidine is a beneficial adjuvant for antiepileptic drugs against maximal electroshock-induced seizures in mice

被引：0
|
作者：
R. M. Kamiński
D. Żółkowska
M. Kozicka
Z. Kleinrok
S. J. Czuczwar
机构：
[1] Isotope Laboratory,
[2] Institute of Agricultural Medicine,undefined
[3] Lublin,undefined
[4] Poland,undefined
[5] Department of Hygiene,undefined
[6] Medical University,undefined
[7] Lublin,undefined
[8] Poland,undefined
[9] Department of Pharmacology and Toxicology,undefined
[10] Medical University,undefined
[11] Lublin,undefined
[12] Poland,undefined
[13] Department of Pathophysiology,undefined
[14] Medical University,undefined
[15] Lublin,undefined
[16] Poland,undefined
来源：
Amino Acids | 2004年 / 26卷
关键词：
Keywords: L-Histidine – Histamine – Antiepileptic drugs – Mice – Epilepsy;
D O I：
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中图分类号：
学科分类号：
摘要：
Endogenous histamine has been reported to be involved in regulation of seizure susceptibility. Enhancement of histamine neurotransmission engendered by L-histidine treatment produces anticonvulsant effects in experimental animals. The present study investigated the influence of L-histidine on the protective effects of carbamazepine and phenytoin against maximal electroshock-induced seizures in mice.
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页码：85 / 89
页数：4
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