Identification and validation of a novel immune-related signature associated with macrophages and CD8 T cell infiltration predicting overall survival for hepatocellular carcinoma

被引:0
作者
Junyu Huo
Liqun Wu
Yunjin Zang
机构
[1] The Affiliated Hospital of Qingdao University,Liver Disease Center
来源
BMC Medical Genomics | / 14卷
关键词
Hepatocellular carcinoma; Immune related gene; Macrophages; CD8 T cell; Prognostic signature;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 109 条
  • [1] Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries J Clin 68 394-424
  • [2] Ferlay J(2020)Advances in molecular classification and precision oncology in hepatocellular carcinoma J Hepatol 72 215-229
  • [3] Soerjomataram I(2018)The immunology of hepatocellular carcinoma Nat Immunol 19 222-232
  • [4] Siegel RL(2017)Current progress in immunotherapy of hepatocellular carcinoma J Hepatol 66 482-484
  • [5] Torre LA(2015)Much more than M1 and M2 macrophages, there are also CD169+ and TCR+ macrophages Front Immunol 6 263-596
  • [6] Jemal A(2015)Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway Int J Oncol 46 587-36
  • [7] Rebouissou S(2018)Cellular and molecular targets for the immunotherapy of hepatocellular carcinoma Mol Cell Biochem 437 13-2502
  • [8] Nault JC(2017)Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial Lancet 389 2492-17
  • [9] Ringelhan M(2019)Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape Mol Camcer 18 1-169
  • [10] Pfister D(2018)ImmPort, toward repurposing of open access immunological assay data for translational and clinical research Sci Dta 5 180015-890