Modification of tetrahydrocarbazoles with pharmacophore ligands by copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition

被引：0
作者：
V. B. Sokolov
A. Yu. Aksinenko
T. A. Epishina
T. V. Goreva
机构：
[1] Russian Academy of Sciences,Institute of Physiologically Active Compounds
来源：
Russian Chemical Bulletin | 2018年 / 67卷
关键词：
azide-containing tetrahydrocarbazoles; -propargyltetrahydrocarbazole; -propargylcarbazole; -propargylphenothiazine; copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition; 1,4-substitutedные 1,2,3-triazoles; conjugates;
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学科分类号：
摘要：
A synthetic approach to the modification of tetrahydrocarbazoles with pharmacophore ligands (carbazole, tetrahydrocarbazole, and phenothiazine) was proposed based on the coppercatalyzed alkyne-azide 1,3-dipolar cycloaddition of azide-containing tetrahydrocarbazoles and propargyl-containing carbazole, tetrahydrocarbazole, and phenothiazine.
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页码：1679 / 1683
页数：4
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