Structural basis of Smoothened regulation by its extracellular domains

被引:0
作者
Eamon F. X. Byrne
Ria Sircar
Paul S. Miller
George Hedger
Giovanni Luchetti
Sigrid Nachtergaele
Mark D. Tully
Laurel Mydock-McGrane
Douglas F. Covey
Robert P. Rambo
Mark S. P. Sansom
Simon Newstead
Rajat Rohatgi
Christian Siebold
机构
[1] Wellcome Trust Centre for Human Genetics,Division of Structural Biology
[2] University of Oxford,Departments of Biochemistry and Medicine
[3] Stanford University School of Medicine,Department of Biochemistry
[4] University of Oxford,Department of Developmental Biology
[5] Diamond Light Source Ltd,undefined
[6] Harwell Science & Innovation Campus,undefined
[7] Washington University School of Medicine,undefined
来源
Nature | 2016年 / 535卷
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学科分类号
摘要
Structural studies show that the activity of the G-protein-coupled receptor Smoothened is modulated by ligand-regulated interactions between its extracellular and transmembrane domains.
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页码:517 / 522
页数:5
相关论文
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