Effects of antioxidants against atherosclerosis

被引：0
作者：
Etsuo Niki
Noriko Noguchi
机构：
[1] National Institute of Advanced Industrial Science and Technology (AIST),Human Stress Signal Research Center
[2] University of Tokyo,Research Center for Advanced Science and Technology
来源：
Molecular and Cellular Biochemistry | 2002年 / 234-235卷
关键词：
antioxidant; atherosclerosis; free radical; lipoxygenase; low density lipoprotein; oxidation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
It is generally accepted that the oxidative modification of low density lipoprotein (LDL) plays a pivotal role in the progression of atherosclerosis. This suggests that the antioxidants which suppress the oxidative modification of LDL should be effective in preventing atherogenesis. This brief article reviews the role and potency of antioxidants against the oxidation of LDL. It is emphasized that the LDL can be oxidized by different oxidants by different mechanisms and the efficacy of antioxidants depends on the type of oxidants.
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页码：19 / 25
页数：6
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