PSMC5 regulates microglial polarization and activation in LPS-induced cognitive deficits and motor impairments by interacting with TLR4

被引:0
|
作者
Wei Bi
Keyao Bao
Xinqi Zhou
Yihui Deng
Xiaoting Li
Jiawei Zhang
Xin Lan
Jiayi Zhao
Daxiang Lu
Yezi Xu
Yanmei Cen
Rui Cao
Mengyang Xu
Wenbin Zhong
Lihong Zhu
机构
[1] The First Affiliated Hospital of Jinan University,Department of Neurology
[2] The First Affiliated Hospital of Jinan University,Clinical Neuoscience Institute
[3] Jinan University,Department of Pathophysiology, School of Medicine
[4] Central Laboratory of the First Affiliated Hospital of Jinan University,Department of Biology
[5] Jinan University,undefined
[6] Guangzhou Key Laboratory for Germ-free Animals and Microbiota Application,undefined
来源
Journal of Neuroinflammation | / 20卷
关键词
Luteolin; Proteasome 26S subunit (PSMC5), ATPase 5; TLR4; Microglia; Synapse; Neuroinflammation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Correction to: Schisandrin B Attenuates Inflammation in LPS-Induced Sepsis through miR-17-5p Downregulating TLR4
    Zhi-Rong Ji
    Wei-Liang Xue
    Ling Zhang
    Inflammation, 2019, 42 : 740 - 740
  • [42] Oxomollugin, an oxidized substance in mollugin, inhibited LPS-induced NF-κB activation via the suppressive effects on essential activation factors of TLR4 signaling
    Nakajima, Yuki
    Tsuboi, Naohide
    Katori, Kumiko
    Waili, Maigunuer
    Nugroho, Alfarius Eko
    Takahashi, Kazunori
    Nishino, Hitomi
    Hirasawa, Yusuke
    Kawasaki, Yoko
    Goda, Yukihiro
    Kaneda, Toshio
    Morita, Hiroshi
    JOURNAL OF NATURAL MEDICINES, 2024, 78 (03) : 568 - 575
  • [43] Effect of the TLR4 Asp299gly polymorphism on LPS-induced cytokine production and Nf-κB activation in mononuclear cells
    Hold, Georgina
    Berry, Susan
    Perez-perez, Guillermo I.
    El-omar, Emad M.
    GASTROENTEROLOGY, 2007, 132 (04) : A217 - A218
  • [44] Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS-Induced Neuroinflammation by Interfering in the TLR4/NF- κ B-MAPK Signaling Pathway in Microglial Cells
    De Sousa J.A.C.
    Azul F.V.C.S.
    De Araújo A.B.
    Tomé R.C.
    Silva F.R.M.
    De Vasconcelos S.M.M.
    Rios F.J.
    Leal L.K.A.M.
    Oxidative Medicine and Cellular Longevity, 2023, 2023
  • [45] Helicobacter pylori LPS-induced gastric mucosal spleen tyrosine kinase (Syk) recruitment to TLR4 and activation occurs with the involvement of protein kinase Cδ
    Slomiany, B. L.
    Slomiany, A.
    INFLAMMOPHARMACOLOGY, 2018, 26 (03) : 805 - 815
  • [46] Catecholamines Attenuate LPS-Induced Inflammation through β2 Adrenergic Receptor Activation- and PKA Phosphorylation-Mediated TLR4 Downregulation in Macrophages
    Wang, Cong
    Feng, Guo-Gang
    Takagi, Junko
    Fujiwara, Yoshihiro
    Sano, Tsuyoshi
    Note, Hideaki
    CURRENT ISSUES IN MOLECULAR BIOLOGY, 2024, 46 (10) : 11336 - 11348
  • [47] NZ suppresses TLR4/NF-κB signalings and NLRP3 inflammasome activation in LPS-induced RAW264.7 macrophages
    Pengjun Xiang
    Tong Chen
    Yi Mou
    Hui Wu
    Peng Xie
    Guo Lu
    Xiaojian Gong
    Qinghua Hu
    Yihua Zhang
    Hui Ji
    Inflammation Research, 2015, 64 : 799 - 808
  • [48] Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway
    Zhang, Haihua
    Lang, Wuying
    Wang, Shiyong
    Li, Binru
    Li, Guangyu
    Shi, Qiumei
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 88
  • [49] Helicobacter pylori LPS-induced gastric mucosal spleen tyrosine kinase (Syk) recruitment to TLR4 and activation occurs with the involvement of protein kinase Cδ
    B. L. Slomiany
    A. Slomiany
    Inflammopharmacology, 2018, 26 : 805 - 815
  • [50] ULINASTATIN PROTECTS AGAINST LPS-INDUCED ACUTE LUNG INJURY BY ATTENUATING TLR4/NF-KB PATHWAY ACTIVATION AND REDUCING INFLAMMATORY MEDIATORS
    Cao, Chao
    Yin, Chengfen
    Shou, Songtao
    Wang, Jun
    Yu, Lechang
    Li, Xuening
    Chai, Yanfen
    SHOCK, 2018, 50 (05): : 595 - 605