Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

被引：0
作者：
Maria T Pallotta
Ciriana Orabona
Claudia Volpi
Carmine Vacca
Maria L Belladonna
Roberta Bianchi
Giuseppe Servillo
Cinzia Brunacci
Mario Calvitti
Silvio Bicciato
Emilia M C Mazza
Louis Boon
Fabio Grassi
Maria C Fioretti
Francesca Fallarino
Paolo Puccetti
Ursula Grohmann
机构：
[1] University of Perugia,Department of Experimental Medicine and Biochemical Sciences
[2] University of Perugia,Department of Clinical and Experimental Medicine
[3] University of Modena and Reggio Emilia,Department of Biomedical Sciences
[4] Bioceros,undefined
[5] Utrecht,undefined
[6] The Netherlands.,undefined
[7] Institute for Research in Biomedicine,undefined
来源：
Nature Immunology | 2011年 / 12卷
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学科分类号：
摘要：
The tryptophan-catalytic activity of IDO in dendritic cells is known to regulate immune responses. Grohmann and co-workers show that IDO also functions as an intracellular signal transducer in response to transforming growth factor-β.
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页码：870 / 878
页数：8
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