Gastrointestinal Features of Parkinson’s Disease

被引：0
作者：
Leslie J. Cloud
James G. Greene
机构：
[1] Emory University,505H Whitehead Biomedical Research Building
[2] Emory University,undefined
来源：
Current Neurology and Neuroscience Reports | 2011年 / 11卷
关键词：
Gastrointestinal; Nonmotor symptoms; Parkinson’s disease; Weight loss; Sialorrhea; Dysphagia; Aspiration; Gastroparesis; Nausea; Vomiting; Bloating; Reflux; Early satiety; Constipation; Defecatory dysfunction; Laxatives; Glycopyrrolate; Atropine; Ipratropium bromide; Botulinum toxin; Polyethylene glycol; Psyllium; Domperidone; Apomorphine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Gastrointestinal (GI) symptoms are among the most common nonmotor manifestations of Parkinson’s disease (PD), and they have many important ramifications for patients. The purpose of this review is to raise awareness of the full spectrum of GI symptoms in PD which include weight loss, sialorrhea, dysphagia, nausea, constipation, and defecatory dysfunction. We will discuss their practical significance, and outline a clear approach to their evaluation and management. A brief discussion about the impacts of commonly used medical and surgical PD therapies on GI symptom manifestation is also included.
引用
收藏
页码：379 / 384
页数：5
相关论文
共 196 条
[1]  
Pfeiffer RF(2003)Gastrointestinal dysfunction in Parkinson’s disease Lancet Neurol. 2 107-16
[2]  
Pfeiffer RF(2011)Gastrointestinal dysfunction in Parkinson’s disease Parkinsonism Relat Disord. 17 10-15
[3]  
Jost WH(2010)Gastrointestinal dysfunction in Parkinson’s Disease J Neurol Sci. 289 69-73
[4]  
Sakakibara R(2008)Bladder and bowel dysfunction in Parkinson’s disease J Neural Transm. 115 443-60
[5]  
Uchiyama T(2009)The second brain and Parkinson’s disease Eur J Neurosci. 30 735-41
[6]  
Yamanishi T(1992)Gastrointestinal dysfunction in Parkinson’s disease: frequency and pathophysiology Neurology. 42 726-32
[7]  
Lebouvier T(2010)Nonmotor symptoms are independently associated with impaired health-related quality of life in Chinese patients with Parkinson’s disease Mov Disord. 25 2740-6
[8]  
Chaumette T(2008)A comprehensive model of health-related quality of life in Parkinson’s disease J Neurol. 255 1580-7
[9]  
Paillusson S(2001)Questionnaire-based assessment of pelvic organ dysfunction in Parkinson’s Disease Auton Neurosci. 92 76-85
[10]  
Edwards LL(2009)The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson’s disease Mov Disord. 24 1641-9
12345678910