Clinical pregnancy in Turner syndrome following re-implantation of cryopreserved ovarian cortex

被引：0
作者：
CE Dunlop
SA Jack
EE Telfer
S. Zahra
RA Anderson
机构：
[1] Edinburgh Royal Infirmary,Simpson’s Centre for Reproductive Health
[2] University of Edinburgh,Institute of Cell Biology and CDBS
[3] Scottish National Blood Transfusion Service,Tissues, Cells & Advanced Therapeutics
[4] University of Edinburgh,MRC Centre for Reproductive Health
来源：
Journal of Assisted Reproduction and Genetics | 2023年 / 40卷
关键词：
Turner syndrome; Ovarian cortex re-implantation; Fertility preservation; Premature ovarian insufficiency;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Turner syndrome (TS) leads to a characteristic phenotype, including premature ovarian insufficiency and infertility. Ovarian tissue cryopreservation (OTC) is becoming an established fertility preservation strategy for both pre- and post-pubertal females and may offer the chance of having a biological family to selected patients with TS. To date, women with TS have had ovarian tissue cryopreserved but there are few reports of autologous re-implantation and none of pregnancy. We herein report, to our knowledge, the first clinical pregnancy in a patient with TS, conceived naturally following re-implantation of cryopreserved ovarian tissue which had been removed soon after spontaneous puberty. This provides proof of concept for OTC as a means of fertility preservation in TS.
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页码：2385 / 2390
页数：5
相关论文
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