Urethral metastasis from non-seminomatous germ cell tumor: A case report

被引：1

作者：

Agarwal V. ^{[1
]}

Wah T. ^{[2
]}

Chilka S. ^{[3
]}

Joffe J. ^{[1
]}

Stark D. ^{[1
]}

机构：

[1] St James's Institute of Oncology, Department of Medical Oncology, Leeds

[2] St James's Institute of Oncology, Department of Radiology, Leeds

[3] St James's Institute of Oncology, Department of Pathology, Leeds

来源：

Journal of Medical Case Reports | / 5卷 / 1期

关键词：

Testicular Cancer; Acute Urinary Retention; Lactate Dehydrogenase Level; Urinary Tract Obstruction; Nonseminomatous Germ Cell Tumor;

D O I：

10.1186/1752-1947-5-12

中图分类号：

学科分类号：

摘要：

Introduction. We present a case of nonseminomatous germ cell tumor of the testes with acute urinary retention secondary to urethral metastasis. This presentation, and similar cases of urethral metastasis from this tumor, have not been reported previously. Case presentation. A 35-year-old Caucasian man presented to hospital with a history of acute urinary retention. On examination he was found to have right testicular enlargement with raised -human chorionic gonadotrophin, serum -fetoprotein and lactate dehydrogenase levels. He underwent radical left inguinal orchidectomy and histology confirmed a nonseminomatous germ cell tumor of the testes. Cystoscopy carried out due to urinary retention showed penile metastasis and the biopsy confirmed metastatic malignant undifferentiated teratoma. Staging computed tomography scan and magnetic resonance imaging of the pelvis showed pulmonary, pelvic nodal, ischial and penile metastasis. The diagnosis of the International Germ Cell Cancer Collaborative Group of poor prognosis metastatic nonseminomatous germ cell tumor was made, following which he received four cycles of bleomycin, etoposide and cisplatin chemotherapy with curative intent. He had a complete marker and an excellent radiological response. He is currently under follow up. Conclusion: The unusual presentation of lymphovascular spread in this case of nonseminomatous germ cell tumor highlights the need to include routine pelvic imaging in the assessment and follow up of testicular cancer. © 2011 Agarwal et al; licensee BioMed Central Ltd.

引用

共 3 条

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[2]

Straub B., Muller M., Schrader M., Heicappell R., Hardung R., Miller K., Recurrent intraluminal ureteral metastasis of a testicular seminoma, Journal of Urology, 164, 2, pp. 443-444, (2000)

[3]

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