Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines

[1] Fritz G(1999)Rho GTPases are over-expressed in human tumors Int J Cancer 81 682-687

[2] Just I(2008)RhoA protein expression in primary breast cancers and matched lymphocytes is associated with progression of the disease Int J Mol Med 22 25-31

[3] Kaina B(2006)Overexpression of RhoA is associated with poor prognosis in hepatocellular carcinoma Eur J Surg Oncol 32 1130-1134

[4] Bellizzi A(2005)Rho GTPase expression in tumourigenesis: evidence for a significant link Bioessays 27 602-613

[5] Mangia A(1995)Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 53-62

[6] Chiriatti A(1999)Interplay between Rac and Rho in the control of substrate contact dynamics Curr Biol 9 640-648

[7] Petroni S(1999)Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior J Cell Biol 147 1009-1022

[8] Quaranta M(1997)Characterization of RAC3, a novel member of the Rho family J Biol Chem 272 20384-20388

[9] Schittulli F(1996)The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1 Cell 85 573-583

[10] Malfettone A(2005)Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells Breast Cancer Res 7 R965-974

[1] Fritz G(1999)Rho GTPases are over-expressed in human tumors Int J Cancer 81 682-687

[2] Just I(2008)RhoA protein expression in primary breast cancers and matched lymphocytes is associated with progression of the disease Int J Mol Med 22 25-31

[3] Kaina B(2006)Overexpression of RhoA is associated with poor prognosis in hepatocellular carcinoma Eur J Surg Oncol 32 1130-1134

[4] Bellizzi A(2005)Rho GTPase expression in tumourigenesis: evidence for a significant link Bioessays 27 602-613

[5] Mangia A(1995)Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 53-62

[6] Chiriatti A(1999)Interplay between Rac and Rho in the control of substrate contact dynamics Curr Biol 9 640-648

[7] Petroni S(1999)Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior J Cell Biol 147 1009-1022

[8] Quaranta M(1997)Characterization of RAC3, a novel member of the Rho family J Biol Chem 272 20384-20388

[9] Schittulli F(1996)The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1 Cell 85 573-583

[10] Malfettone A(2005)Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells Breast Cancer Res 7 R965-974