Molecular mechanism of pancreatic cancer—understanding proliferation, invasion, and metastasis

被引:0
作者
André L. Mihaljevic
Christoph W. Michalski
Helmut Friess
Jörg Kleeff
机构
[1] Technische Universität München,Chirurgische Klinik und Poliklinik, Klinikum rechts der Isar
来源
Langenbeck's Archives of Surgery | 2010年 / 395卷
关键词
Pancreatic cancer; Pathogenesis; Genetic alterations; Pancreatic stellate cells; Desmoplasia; Signaling pathways; Metastasis;
D O I
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中图分类号
学科分类号
摘要
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页码:295 / 308
页数:13
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  • [1] Alexakis N(2004)Current standards of surgery for pancreatic cancer Br J Surg 91 1410-1427
  • [2] Halloran C(2007)Cancer statistics CA Cancer J Clin 57 43-66
  • [3] Raraty M(2002)Pancreatic stem cells J Pathol 197 519-526
  • [4] Ghaneh P(2000)Genetic progression in the pancreatic ducts Am J Pathol 156 1821-1825
  • [5] Sutton R(2007)Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN Cancer Cell 12 266-279
  • [6] Neoptolemos JP(1985)Ductal metaplasia of human exocrine pancreas and its association with carcinoma Cancer Res 45 1285-1290
  • [7] Jemal A(1999)Sequential accumulation of K-ras mutations and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy Ann Surg 230 501-509
  • [8] Siegel R(1990)TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas Cell 61 1137-1146
  • [9] Ward E(1990)Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast Cell 61 1121-1135
  • [10] Murray T(2001)A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease Genes Dev 15 286-293