Efficacy and safety of proxalutamide (GT0918) in severe or critically ill patients with COVID-19: study protocol for a prospective, open-label, single-arm, single-center exploratory trial

被引：0
|
作者：
Dawei Yang
Minjie Ju
Hao Wang
Yichen Jia
Xiaodan Wang
Hao Fang
Jia Fan
机构：
[1] Zhongshan Hospital Fudan University,Department of Pulmonary and Critical Care Medicine
[2] Zhongshan Hospital (Xiamen),Department of Pulmonary and Critical Care Medicine
[3] Fudan University,Department of Critical Care Medicine
[4] Shanghai Engineer & Technology Research Center of Internet of Things for Respiratory Medicine,Department of Thoracic Surgery
[5] Zhongshan Hospital Fudan University,Department of Urology
[6] Zhongshan Hospital Fudan University,Department of Anesthesiology
[7] Zhongshan Hospital Fudan University,Department of Anesthesiology
[8] Zhongshan Hospital Fudan University,Department of Liver Surgery and Transplantation
[9] Minhang Hospital,Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences
[10] Fudan University,undefined
[11] Liver Cancer Institute,undefined
[12] Zhongshan Hospital,undefined
[13] Fudan University,undefined
[14] Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education，Fudan University,undefined
[15] Fudan University,undefined
来源：
BMC Pharmacology and Toxicology | / 24卷
关键词：
COVID-19; Critical ill COVID-19; Proxalutamide; Severe COVID-19;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Clinical Characteristics of Patients with Severe and Critical COVID-19 in Wuhan: A Single-Center, Retrospective Study
    Zhaohui Chen
    Junyi Hu
    Lilong Liu
    Youpeng Zhang
    Dandan Liu
    Ming Xiong
    Yi Zhao
    Ke Chen
    Yu-Mei Wang
    Infectious Diseases and Therapy, 2021, 10 : 421 - 438
  • [42] Tocilizumab for the treatment of adult patients with severe COVID-19 pneumonia: A single-center cohort study
    Fernandez-Ruiz, Mario
    Lopez-Medrano, Francisco
    Perez-Jacoiste Asin, Maria Asuncion
    Maestro de la Calle, Guillermo
    Bueno, Hector
    Manuel Caro-Teller, Jose
    Catalan, Mercedes
    de la Calle, Cristina
    Garcia-Garcia, Rocio
    Gomez, Carlos
    Laguna-Goya, Rocio
    Lizasoain, Manuel
    Martinez-Lopez, Joaquin
    Origuen, Julia
    Luis Pablos, Jose
    Ripoll, Mar
    San Juan, Rafael
    Trujillo, Hernando
    Lumbreras, Carlos
    Maria Aguado, Jose
    JOURNAL OF MEDICAL VIROLOGY, 2021, 93 (02) : 831 - 842
  • [43] Genomic insight into COVID-19 severity in MAFLD patients: a single-center prospective cohort study
    Buchynskyi, Mykhailo
    Oksenych, Valentyn
    Kamyshna, Iryna
    Budarna, Olena
    Halabitska, Iryna
    Petakh, Pavlo
    Kamyshnyi, Oleksandr
    FRONTIERS IN GENETICS, 2024, 15
  • [44] Colon ischemia in patients with severe COVID-19: a single-center retrospective cohort study of 20 patients
    Yang, Cui
    Hakenberg, Priska
    Weiss, Christel
    Herrle, Florian
    Rahbari, Nuh
    Reissfelder, Christoph
    Hardt, Julia
    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2021, 36 (12) : 2769 - 2773
  • [45] Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients-An Open-Label Phase II Clinical Trial
    Rastvorceva, Rada M. Grubovic
    Useini, Sedula
    Stevanovic, Milena
    Demiri, Ilir
    Petkovic, Elena
    Franchini, Massimo
    Focosi, Daniele
    LIFE-BASEL, 2022, 12 (10):
  • [46] Efficacy of Tocilizumab in Patients with a Moderate and Severe COVID-19: A Retrospective Single Center Cohort Study
    Bolukcu, Sibel
    KarakuS, Dilara
    Okay, Gulay
    Akkoyunlu, Yasemin
    Sumbul, Bilge
    Durdu, Bulent
    Koc, Meliha Meric
    Aslan, Turan
    MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, 2021, 10
  • [47] COVID-19 vaccination in psoriasis patients receiving systemic treatment: A prospective single-center study
    Lodde, Georg Christian
    Krefting, Frederik
    Placke, Jan-Malte
    Schneider, Lea
    Fiedler, Melanie
    Dittmer, Ulf
    Becker, Juergen Christian
    Hoelsken, Stefanie
    Schadendorf, Dirk
    Ugurel, Selma
    Sondermann, Wiebke
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [48] Safety and efficacy of COVID-19 vaccination in the Chinese population with pulmonary lymphangioleiomyomatosis: a single-center retrospective study
    Wang, Weilin
    Zhou, Jingdong
    Kong, Xuetao
    Wang, Yixuan
    Wu, Qixian
    Gong, Xiaoqing
    Tai, Jingye
    Pan, Yingxin
    Huang, Hongyuan
    Zhao, Zhen
    Jiang, Mei
    Liu, Jie
    ORPHANET JOURNAL OF RARE DISEASES, 2024, 19 (01)
  • [49] Efficacy and Safety of Therapeutic Versus Prophylactic Dose of Anticoagulation in Hospitalized Patients with Severe COVID-19 Pneumonia and Coagulopathy: An Open-Label, Randomized Controlled Trial
    Adrian, L. H.
    Hutomo, S. A.
    Negari, A. D. S.
    EUROPEAN HEART JOURNAL SUPPLEMENTS, 2021, 23 (0F)
  • [50] Safety and efficacy of pamrevlumab (FG-3019) in patients with COVID-19 pneumonia: an open-label, randomized, parallel-arm phase 2 study
    Sgalla, G.
    Simonetti, J.
    Gualano, G.
    Leone, P. Maria
    Comes, A.
    Verdirosi, D.
    Poole, L.
    Kouchakji, E.
    Palmieri, F.
    Richeldi, L.
    Simonetti, J.
    EUROPEAN RESPIRATORY JOURNAL, 2022, 60
12345